Examining the link between muscle enzyme levels and pelvic floor strength in new mothers

Correlation Between Creatine Phosphokinase and Pelvic Floor Muscle Strength in Postnatal Women

Observational Cairo University · NCT06502392

This study is testing if the levels of a muscle enzyme in new mothers are related to the strength of their pelvic floor muscles after giving birth.

Quick facts

Study typeObservational
Enrollment84 (estimated)
Ages25 Years to 35 Years
SexFemale
SponsorCairo University Academic / other
Locations1 site (Giza)
Trial IDNCT06502392 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the correlation between creatine phosphokinase (CPK) levels and pelvic floor muscle strength in postpartum women who delivered vaginally. By measuring CPK levels within the first six weeks after delivery and assessing pelvic floor strength, the study seeks to enhance understanding of pelvic floor disorders, which affect many women postnatally. The findings could provide valuable insights for improving women's health physical therapy and treatment approaches for pelvic floor disorders.

Who should consider this trial

Good fit: Ideal candidates are postpartum women aged 25 to 35 who delivered vaginally and have a BMI under 30.

Not a fit: Patients with pelvic floor dysfunction, previous surgeries affecting the pelvic area, or other significant health issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to better diagnostic and therapeutic strategies for pelvic floor disorders in postpartum women.

How similar studies have performed: While this specific correlation has not been previously explored, related studies on pelvic floor disorders and muscle enzyme levels suggest potential for meaningful insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Post-partum women who delivered vaginally.
* Their ages will range from 25 to 35 years old.
* Their body mass index (BMI) will be \<30 Kg/m2.
* CPK will be measured within the first six weeks (2nd-5th weeks) after delivery for all women.

Exclusion Criteria:

* Any dysfunction or associated injury or any pathological conditions which may affect the result of the study as cardiac abnormalities, thyroid dysfunction recurrent urinary tract infections, uncontrolled hypertension or diabetes mellitus.
* History of pelvic inflammatory disease, myoma and tumors, pelvic infection, ovarian cyst, any gynecological disease, any hormonal abnormality and any psychological problem.
* Pelvic floor dysfunction: genital prolapse, incontinence.
* Previous surgical operations as hysterectomy.
* Inability to understand the written and verbal instructions.

Where this trial is running

Giza

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pelvic FloorRupture, OldPelvic floor strengthCreatine phosphokinasePostnatal women
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.