Examining the link between CT scans, bone density, and hearing loss in otosclerosis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the relationship between temporal bone CT findings, bone mineral density (BMD), and hearing loss in adults diagnosed with otosclerosis. Researchers will compare patients with otosclerosis to a control group without the condition to assess correlations between CT density values and hearing loss severity. Participants will undergo BMD assessments, serum vitamin D level measurements, and audiological testing, utilizing existing CT scans from routine evaluations. The study seeks to uncover potential systemic bone metabolism markers associated with otosclerosis.

Why it matters

Who can join: the full rules

Inclusion Criteria (Otosclerosis Group):

* Adults diagnosed with otosclerosis based on audiological and clinical assessment
* Patients with available high-resolution CT scans and audiological data
* Individuals who have undergone stapedectomy or stapedotomy surgery
* Availability of bone mineral density and serum vitamin D data

Inclusion Criteria (Control Group):

* Patients without otosclerosis but with temporal CT imaging for other indications
* No history of conductive or mixed hearing loss
* Availability of BMD and vitamin D data

Exclusion Criteria:

* History of primary metabolic bone diseases (osteoporosis, Paget's disease)
* Use of medications affecting bone metabolism (bisphosphonates, corticosteroids)
* History of chronic otitis media or prior ear surgeries
* Patients who received head and neck radiotherapy

Where it's running

• Hacettepe University Hospitals
  Ankara, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: İbrahim Emir Yeşil, MD
• Email: iemiryesil@gmail.com
• Phone: +905019103056

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.