Examining the link between a specific gene and telomere length in lung diseases
MucinB5 rs (35705950) Gene Polymorphism and Leucocytes Telomere Length in Relation to Interstitial Lung Diseases.
This study is trying to see if a specific gene affects the length of certain protective parts of cells in adults with interstitial lung diseases.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06498141 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between the Mucin B5 rs (35705950) gene polymorphism and the length of leukocyte telomeres in patients with interstitial lung diseases. By analyzing genetic variations and their potential impact on telomere length, the study aims to enhance understanding of the biological mechanisms underlying these lung conditions. Participants will be adults over 18 years old diagnosed with interstitial lung diseases, while those with certain exclusions such as emphysema or active cancer will not be eligible.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old diagnosed with interstitial lung diseases.
Not a fit: Patients with emphysema, obstructive lung diseases, active cancer, end-stage renal failure, or liver cell failure may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into genetic factors influencing interstitial lung diseases, potentially leading to improved diagnostic and therapeutic strategies.
How similar studies have performed: While this study explores a specific genetic polymorphism in relation to telomere length, similar studies have shown varying degrees of success in linking genetic factors to lung disease outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: This study will include patients with interstitial lung diseases aged above 18 years old. Exclusion Criteria: * patients with emphysema or obstructive lung diseases. * patients with active cancer * End stage renal failure (GFR \< 30 ml/min) or on dialysis * Liver cell failure
Where this trial is running
Sohag
- Sohag university hosoital — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: Amera Morad Foad, professor
- Email: ameramoradfoad@gmail.com
- Phone: +201006591449
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.