Examining the effects of dexmedetomidine on eye pressure during spine surgeries
Effects of Systemic Administration of Dexmedetomidine on Intraocular Pressure During Scheduled Spine Surgeries in a Prone Position. Prospective, Randomized, Double-blinded Study.
NA · Attikon Hospital · NCT04628663
This study is testing whether a sedative called dexmedetomidine can help keep eye pressure stable during spine surgeries for adults.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Attikon Hospital (other) |
| Locations | 1 site (Athens, Attica) |
| Trial ID | NCT04628663 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates how dexmedetomidine, a sedative, affects intraocular pressure (IOP) in patients undergoing elective spine surgeries while in a prone position under general anesthesia. It is a prospective, randomized, placebo-controlled, double-blinded trial involving adult patients classified as ASA physical status I, II, or III. Participants will be randomly assigned to receive either dexmedetomidine or normal saline, with IOP measurements taken during the procedure to assess the drug's impact. The study aims to provide insights into managing IOP during surgeries that may pose risks to patients with eye conditions.
Who should consider this trial
Good fit: Ideal candidates include adult patients scheduled for elective spine surgery in a prone position under general anesthesia.
Not a fit: Patients with previous eye surgery, preexisting eye diseases, or unstable hemodynamics may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management of intraocular pressure during spine surgeries, potentially reducing complications for patients with eye concerns.
How similar studies have performed: While the specific use of dexmedetomidine for IOP management during spine surgery may be novel, similar studies have shown promising results in other surgical contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients undergoing scheduled spine surgery performed in prone position under general anaesthesia Exclusion Criteria: * Patients who refuse to be a part of the study * Patients with previous eye surgery * Preexisting eye disease (e.g glaucoma) * Allergy to the study drug or any drug which is in the trial * Preoperative unstable hemodynamics
Where this trial is running
Athens, Attica
- 2nd Department of Anesthesiology, Attikon University Hospital — Athens, Attica, Greece (RECRUITING)
Study contacts
- Study coordinator: Paraskevi Matsota, Prof
- Email: matsota@yahoo.gr
- Phone: 6945544563
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Intraocular Pressure