Examining the effects of anesthesia on brain development in children with congenital scoliosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the potential long-term neurocognitive effects of general anesthesia exposure in children diagnosed with congenital scoliosis. It aims to assess whether single or multiple long-duration anesthesia exposures during posterior scoliosis correction surgery impact cognitive function and behavior. The study will involve children aged 6 to 16 years, evaluating their neurodevelopmental outcomes post-anesthesia. The findings could provide critical insights into the safety of anesthesia in this vulnerable population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed with congenital scoliosis
* 6-16 years old at the time of assessment

Exclusion Criteria:

* Cognitive impairment caused by congenital, traumatic or other reasons;
* Existence of mental or psychological disorders;
* There are factors that may affect neurological development, including any known central nervous system disease, neurological injury, or history of neonatal asphyxia;
* Unable to cooperate with cognitive function tests;
* The child is unable to communicate in Chinese.

Where it's running

• Peking Union Medical College Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Lulu Ma, Dr. — Peking Union Medical College Hospital
• Study coordinator: Lulu Ma, Dr.
• Email: malulu@pumch.cn
• Phone: 0086-10-13811049619

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.