Examining spinal alignment changes after hip and knee replacement surgeries
Official title: Knee-Hip-Spine Harmony: The Relationship Between Sagittal Spinal Alignment in Total Hip/Knee Arthroplasty
Run by China Medical University Hospital · NCT05685706 · Data updated 2026-11-12
This study looks at how hip and knee replacement surgeries affect the alignment of the spine in people with osteoarthritis over the course of a year.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | China Medical University Hospital Academic / other |
| Locations | 1 site (Taichung, North District) |
| Status | Recruiting |
| Started | July 7, 2021 |
| Main results expected | December 31, 2031 |
| Study ends | December 31, 2031 |
| Registry record updated | January 17, 2023 |
| Trial ID | NCT05685706 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include elderly patients with primary degenerative arthritis of the knee or hip who have undergone total hip or knee replacement surgery.
✕Probably not a fit
Patients with previous hip or spine surgeries, significant scoliosis, or rheumatoid arthritis lesions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the relationship between sagittal spinal alignment and total hip or knee arthroplasty in patients suffering from osteoarthritis. It aims to assess how these surgeries impact trunk parameters and whether they lead to improvements or deteriorations in spinal alignment. The study focuses on patients who have undergone hip or knee replacement surgery and tracks their spinal alignment over a follow-up period of at least one year. By understanding these relationships, the study seeks to provide insights into optimizing surgical outcomes for patients with concurrent spinal and joint issues.
Why it matters
Potential benefit: If successful, this study could enhance post-surgical outcomes for patients undergoing hip or knee replacements by improving understanding of spinal alignment.
How similar studies have gone: While there is limited research specifically on the relationship between THA/TKA and spinal alignment, similar studies in related areas have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Primary degenerative arthritis of the knee or hip 2. Those who have undergone artificial knee or hip replacement surgery 3. Follow up surgery for at least 1 year 4. Track the whole trunk lower limb sagittal plane coronal aligament before and after surgery Exclusion Criteria: 1. Previous hip surgery 2. Previous spine surgery 3. Contracture after hip fusion surgery 4. Scoliosis over 10 degrees combined with neuropathy 5. Patients with flexion contracture after knee joint surgery 6. Rheumatoid arthritis lesions
Where it's running
-
China Medical University Hospital
Taichung, North District, Taiwan Recruiting
Study contacts
- Study coordinator: Chun-Hao Tsai, PhD
- Email: ritsai8615@gmail.com
- Phone: 04-22052121
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.