Examining spinal alignment changes after hip and knee replacement surgeries

Knee-Hip-Spine Harmony: The Relationship Between Sagittal Spinal Alignment in Total Hip/Knee Arthroplasty

China Medical University Hospital · NCT05685706

This study looks at how hip and knee replacement surgeries affect the alignment of the spine in people with osteoarthritis over the course of a year.

Quick facts

Study typeObservational
Enrollment300 (estimated)
SexAll
SponsorChina Medical University Hospital (other)
Locations1 site (Taichung, North District)
Trial IDNCT05685706 on ClinicalTrials.gov

What this trial studies

This observational study investigates the relationship between sagittal spinal alignment and total hip or knee arthroplasty in patients suffering from osteoarthritis. It aims to assess how these surgeries impact trunk parameters and whether they lead to improvements or deteriorations in spinal alignment. The study focuses on patients who have undergone hip or knee replacement surgery and tracks their spinal alignment over a follow-up period of at least one year. By understanding these relationships, the study seeks to provide insights into optimizing surgical outcomes for patients with concurrent spinal and joint issues.

Who should consider this trial

Good fit: Ideal candidates include elderly patients with primary degenerative arthritis of the knee or hip who have undergone total hip or knee replacement surgery.

Not a fit: Patients with previous hip or spine surgeries, significant scoliosis, or rheumatoid arthritis lesions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance post-surgical outcomes for patients undergoing hip or knee replacements by improving understanding of spinal alignment.

How similar studies have performed: While there is limited research specifically on the relationship between THA/TKA and spinal alignment, similar studies in related areas have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Primary degenerative arthritis of the knee or hip
2. Those who have undergone artificial knee or hip replacement surgery
3. Follow up surgery for at least 1 year
4. Track the whole trunk lower limb sagittal plane coronal aligament before and after surgery

Exclusion Criteria:

1. Previous hip surgery
2. Previous spine surgery
3. Contracture after hip fusion surgery
4. Scoliosis over 10 degrees combined with neuropathy
5. Patients with flexion contracture after knee joint surgery
6. Rheumatoid arthritis lesions

Where this trial is running

Taichung, North District

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cases Who Received TKA/THA, Total hip/knee arthroplasty

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.