Examining silicone particles in breast implant capsules

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the presence of silicone particles in the capsules surrounding breast implants, which can occur due to silicone leakage. It aims to understand the inflammatory response triggered by these particles, which may lead to complications such as granuloma formation and breast pain. The study involves digitizing histological slides from patients who underwent surgical revision of their breast implants at CHU-Brugmann Hospital between January 2013 and October 2023. By analyzing these samples, researchers hope to gain insights into the biological effects of silicone particles on surrounding tissues.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients admitted and operated at CHU-Brugmann Hospital (Horta \& Brien)
* Surgery between January 2013 and October 2023
* Type of surgery: surgical revision of their breast implants requiring partial or complete sampling of the peri-prosthetic capsule.

Exclusion Criteria:

- None

Where it's running

• CHU Brugmann
  Brussels, Belgium Recruiting

Study contacts

• Principal investigator: Socorro Ortiz, MD — CHU Brugmann
• Study coordinator: Christophe Al Sammour
• Email: Christophe.ALSAMMOUR@chu-brugmann.be
• Phone: 32204773997

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Renal rehabilitation with low-dialysate-flow daily hemodialysis for people on hemodialysis

  This tests whether combining a tailored rehab program (exercise + nutrition) with low-dialysate-flow daily hemodialysis helps people on hemodialysis who are at risk of muscle loss (sarcopenia).

  Recruiting Brugmann University Hospital · Brussels · NCT07413315

• Combined processed EEG (PSi) and near-infrared spectroscopy (NIRS) monitoring to prevent postoperative cognitive problems after heart surgery

  This trial will test whether using both processed EEG (PSi) and near-infrared spectroscopy (NIRS) during cardiac surgery with cardiopulmonary bypass can reduce postoperative cognitive disorders in adults.

  Recruiting Brugmann University Hospital · Brussels · NCT07267416

• Median nerve stimulation with EEG and SedLine to detect motor brain activity during propofol anesthesia

  This test uses painless median nerve stimulation plus EEG and SedLine monitoring to see if it can detect movement attempts in right-handed adults having general anesthesia with propofol.

  Recruiting Brugmann University Hospital · Brussels · NCT07267403

• Identifying autoantibodies before immune therapy for cancer

  This study is testing if certain antibodies in the blood can help predict if cancer patients will have side effects from immune therapy and how well the treatment might work for them.

  Recruiting at 3 sites Brugmann University Hospital · Brussels and 2 other locations · NCT06993727

• Understanding fatigue after a first ischemic stroke

  This project will try to see if measures of heart rhythm, blood tests, and brain scans can explain why adults who recently had a first ischemic stroke develop ongoing fatigue.

  Recruiting at 2 sites Brugmann University Hospital · Brussels and 1 other locations · NCT06292377

• Registry for kidney health during pregnancy

  This study is trying to understand how kidney diseases affect pregnancy and the health of mothers by collecting information from women before, during, and after their pregnancies.

  Recruiting Brugmann University Hospital · Brussels · NCT06067867

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.