Examining side effects of antibiotics for bone and joint infections
Prospective Study : Side Effects of Antibiotics in Bone and Joint Infections
This study looks at how long-term use of antibiotics affects the side effects and quality of life for adults with bone and joint infections.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Tours Academic / other |
| Locations | 1 site (Tours) |
| Trial ID | NCT05927311 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the frequency, severity, and impact on quality of life of adverse effects associated with long-term antibiotic therapy in patients with bone and joint infections. Patients over 18 years old with microbiologically proven infections requiring at least six weeks of antibiotic treatment will be followed for one year. The study aims to enhance the understanding of how prolonged antibiotic use affects patients, potentially leading to improved management strategies for osteoarticular infections.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 with microbiologically confirmed bone or joint infections requiring long-term antibiotic therapy.
Not a fit: Patients who do not require prolonged antibiotic therapy or have conditions unrelated to bone or joint infections may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better management of bone and joint infections by minimizing adverse effects from antibiotic treatments.
How similar studies have performed: While there is limited literature on the specific adverse effects of long-term antibiotic therapy for bone and joint infections, similar studies have highlighted the importance of understanding treatment side effects.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient over 18 years of age * Microbiologically proven osteoarticular infection with or without material, requiring antibiotic therapy (single or multiple) of 6 weeks or more * Oral antibiotic therapy (minimum 4 weeks) Exclusion Criteria: * Opposition to data processing * Patient under guardianship or trusteeship
Where this trial is running
Tours
- University Hospital — Tours, France (Recruiting)
Study contacts
- Principal investigator: Marion LACASSE — CHRU de Tours
- Study coordinator: Marion LACASSE
- Email: m.lacasse@chu-tours.fr
- Phone: 0247476028
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.