Examining retinal blood vessels in patients undergoing heart surgery
Retinal Microvascular Network and Coronary Revascularization Surgery at the Dijon University Hospital: Pilot Study
This study is testing if looking at tiny blood vessels in the eye can help predict how well patients will do after heart surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire Dijon Academic / other |
| Locations | 1 site (Dijon) |
| Trial ID | NCT05315349 on ClinicalTrials.gov |
What this trial studies
This study investigates the relationship between the retinal microvascular network and outcomes in patients undergoing myocardial revascularization surgery. It utilizes non-invasive imaging techniques, specifically optical coherence tomography angiography (OCT-A), to assess the microvascular status of the retina as a potential indicator of systemic vascular health. By correlating retinal vessel health with surgical outcomes, the study aims to improve risk stratification and management of cardiovascular complications associated with heart surgery.
Who should consider this trial
Good fit: Ideal candidates include adult patients scheduled for myocardial revascularization surgery at the Dijon University Hospital who can provide informed consent.
Not a fit: Patients with acute circulatory collapse, macular diseases, or those unable to consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance preoperative assessments and reduce cardiovascular complications in patients undergoing heart surgery.
How similar studies have performed: While the use of retinal imaging in cardiovascular risk assessment is emerging, this specific approach remains novel and has not been extensively tested in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patient who has given oral, free and informed consent * Patient who is to undergo cardiac surgery for myocardial revascularization (coronary bypass surgery) with extracorporeal circulation at the Dijon University Hospital Exclusion Criteria: * Patient not covered by national health insurance * Patient subject to a measure of legal protection (curatorship, guardianship) * Acute circulatory collapse prior to surgery (amine, inotrope, circulatory assistance) preventing preoperative OCT-A * Patient with macular disease (age-related macular degeneration, diabetic maculopathy, vascular occlusion) * Pregnant, parturient or breastfeeding women * Adult unable to express consent
Where this trial is running
Dijon
- Chu Dijon Bourgogne — Dijon, France (Recruiting)
Study contacts
- Study coordinator: Louis ARNOULD
- Email: louis.arnould@chu-dijon.fr
- Phone: 03.80.29.37.56
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.