Examining quality of life in patients with diverticular disease undergoing surgery

Quality of Life and Surgery in Diverticular Disease

Observational University of Aarhus · NCT05393609

This study looks at how surgery for diverticular disease affects the quality of life for patients compared to those who choose not to have surgery.

Quick facts

Study typeObservational
Enrollment250 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Aarhus Academic / other
Locations1 site (Randers, Central Jutland)
Trial IDNCT05393609 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients with chronic diverticular disease who are referred to surgical clinics in Denmark. It aims to assess the quality of life and patient-related outcomes following elective laparoscopic sigmoidectomy compared to conservative treatment. Patients will complete questionnaires at the start of the study and again after one year, with additional follow-ups for those who undergo surgery. The study will not alter treatment decisions but will evaluate current practices in managing diverticular disease.

Who should consider this trial

Good fit: Ideal candidates are patients referred to surgical clinics for chronic diverticular disease with confirmed colonic diverticula.

Not a fit: Patients with previous colorectal surgeries, cancer, inflammatory bowel disease, or psychiatric disorders affecting questionnaire responses may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into how elective surgery impacts the quality of life for patients with chronic diverticular disease.

How similar studies have performed: While there is existing literature on the impact of surgical interventions on quality of life in diverticular disease, this study's specific observational approach is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Referred to surgical clinic due to diverticular disease
* Colonic diverticula verified by CT or endoscopy

Exclusion Criteria:

* Previous colonic resection other than appendectomy
* Previous or current colorectal cancer
* Previous or current disseminated cancer
* Inflammatory bowel disease
* Psychiatric disorder influencing the ability to answer questionnaires
* Inadequate Danish

Where this trial is running

Randers, Central Jutland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Diverticulitis ColonQuality of LifeDiverticular Disease of Left Side of Colon
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.