Examining PICC insertion sites and complications in neonates

Peripherally Inserted Central Venous Catheter Insertion Site and Complication Rates in Neonates

Not applicable Interventional University of Calgary · NCT03474978

This study looks at how the location where a special IV is placed in newborns affects the chances of problems that might require it to be taken out.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment320 (estimated)
AgesN/A to 4 Months
SexAll
SponsorUniversity of Calgary Academic / other
Locations1 site (Calgary, Alberta)
Trial IDNCT03474978 on ClinicalTrials.gov

What this trial studies

This study investigates the relationship between the site of peripherally inserted central catheters (PICC) and the rate of complications that lead to their removal in neonates admitted to the neonatal intensive care unit (NICU). By analyzing data from neonates of various gestational ages, the study aims to identify any significant associations that could inform best practices for PICC insertion. The research will focus on neonates who have venous access available in both the upper and lower body, ensuring a comprehensive evaluation of insertion sites.

Who should consider this trial

Good fit: Ideal candidates for this study are neonates of all gestational ages who are admitted to the NICU and require PICC line insertion.

Not a fit: Patients with local infections at the insertion site or significant anatomical anomalies may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved PICC insertion practices, reducing complications and enhancing care for neonates.

How similar studies have performed: While there may be studies on PICC complications, this specific focus on insertion site associations in neonates is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Neonates of all gestational ages admitted to Foothills Medical Centre and Alberta Children's Hospital Neonatal Intensive Care Unit (NICU)
2. Peripherally inserted central venous catheter (PICC) line insertion planned as part of NICU care
3. Venous access available in both upper(above umbilicus) and lower body

Exclusion Criteria:

1. Local infection at potential site of insertion
2. Hemangioma, lymphangioma or malformations in the region of insertion
3. Major chromosomal anomalies

Where this trial is running

Calgary, Alberta

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Catheterization, Peripheral
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.