Examining Pediatric Palliative Care for Children with Brain Tumors

Assessment of the Presence of Symptoms of End-of-life Discomfort and Their Management in Children With a Primary Brain Tumor in the Grand Est Region. Impact of the Development of Pediatric Palliative Care

University Hospital, Strasbourg, France · NCT05660499

This study looks at how care for children with brain tumors at the end of their lives has changed over the past decade to see if palliative care has improved their comfort and quality of life.

Quick facts

Study typeObservational
Enrollment40 (estimated)
Ages1 Year to 17 Years
SexAll
SponsorUniversity Hospital, Strasbourg, France (other)
Locations1 site (Strasbourg)
Trial IDNCT05660499 on ClinicalTrials.gov

What this trial studies

This observational study aims to compare the occurrence and management of end-of-life symptoms in children who died from primary brain tumors during two distinct periods, 2009-2010 and 2019-2020. It focuses on children under 17 years of age who received care in specific Pediatric Oncology departments in France. The study seeks to evaluate how the integration of palliative care has evolved and its impact on symptom management and quality of life for these patients and their families. By analyzing data from these two time frames, the study hopes to identify improvements in care practices and outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are children under 17 years old who suffered from a primary brain tumor and died during the specified periods.

Not a fit: Patients who may not benefit from this study include those whose parents have refused the reuse of their personal data for research purposes or those with brain tumors secondary to another cancer.

Why it matters

Potential benefit: If successful, this study could enhance the quality of palliative care provided to children with brain tumors, leading to better symptom management and improved quality of life for patients and their families.

How similar studies have performed: Other studies have shown success in integrating palliative care into pediatric oncology, indicating that this approach may lead to improved outcomes, although this specific comparison of time periods is less common.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria:

* Patient less than 17 years of age
* Suffering from a primary brain tumor
* Died during the period 2009-2010 or during the period 2019-2020
* Follow-up in one of the Pediatric Oncology departments participating in the study (Strasbourg, Besançon, Dijon, Nancy and Reims)
* Absence of refusal expressed in the medical file by the parents or the holder(s) of parental authority concerning the reuse of the child's personal data for research purposes.

Exclusion criteria:

* Refusal expressed in the medical file by the parents or the holder(s) of parental authority concerning the reuse of the child's personal data for research purposes
* Patient with a brain tumor secondary to another cancer

Where this trial is running

Strasbourg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Primary Brain Tumor, Pediatric Palliative Care

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.