Examining non-invasive ventilation for bronchial dilatation disease

Study of the Use of Non-invasive Ventilation in Bronchial Dilatation Disease (BRONCHINIV)

Observational Centre Hospitalier Intercommunal Creteil · NCT06987461

This study looks at how well long-term non-invasive ventilation helps people with bronchial dilatation disease manage their symptoms and stay out of the hospital.

Quick facts

Study typeObservational
Enrollment70 (estimated)
Ages18 Years and up
SexAll
SponsorCentre Hospitalier Intercommunal Creteil Academic / other
Locations5 sites (Créteil and 4 other locations)
Trial IDNCT06987461 on ClinicalTrials.gov

What this trial studies

This observational study collects medical record data to analyze the characteristics of patients with bronchial dilatation disease who are treated with long-term non-invasive ventilation (NIV). It aims to assess epidemiological factors, reasons for initiating NIV, and methods of NIV adjustment. The study is retrospective and focuses on understanding the effectiveness of NIV in managing exacerbations, hospital admissions, and mortality rates among these patients. By analyzing existing medical records, the study seeks to improve patient management strategies.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years with a predominant diagnosis of bronchiectatic disease confirmed by CT scans, who have been treated with long-term NIV.

Not a fit: Patients with cystic fibrosis, predominant diagnoses of COPD or asthma, or other specified conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the management and treatment outcomes for patients with bronchial dilatation disease using non-invasive ventilation.

How similar studies have performed: While this study explores a relatively untested area regarding the efficacy of NIV in bronchial dilatation disease, similar observational studies have shown promise in understanding treatment outcomes in other respiratory conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients over 18 years
* Predominant diagnosis of bronchiectatic disease, excluding cystic fibrosis, confirmed by computed tomography
* Introduction of long-term NIV at a given point in the patient's care

Exclusion Criteria:

* Patient's opposition to participating in this study
* Cystic fibrosis
* Predominant diagnosis of COPD or asthma, traction bronchiectasis, bronchiectasis resulting from focal endobronchial lesion, sarcoidosis or active allergic bronchopulmonary aspergillosis.

Where this trial is running

Créteil and 4 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Bronchial Dilatation DiseaseBronchectasiebronchial dilatation diseaseNon-invasive ventilationefficiency
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.