Examining Neutrophils in Sepsis Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the characteristics of neutrophils found in the blood and secretions from the breathing tubes of patients suffering from sepsis. Sepsis is a severe infection that can affect multiple body systems, and neutrophils play a crucial role in the immune response. By analyzing these white blood cells, researchers hope to understand their behavior and potential harmful effects in sepsis, which could lead to the development of targeted therapies to mitigate lung injury caused by these cells.

Why it matters

Who can join: the full rules

Case Inclusion Criteria:

* sepsis patient in the ICU with a breathing tube

Control Inclusion Criteria:

* scheduled for an elective surgical procedure and need preoperative blood draw or will have an intravenous catheter placed for the purpose of their surgical procedure
* Plan to have endotracheal tube for planned procedures.

Exclusion Criteria:

* On chronic immunosuppressive drugs such as chronic corticosteroid use, or preexisting immunodeficiency diseases (oncology patients, patients with transplantation)

Where it's running

• Boston Children's Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Koichi Yuki, MD — Boston Children's Hospital
• Study coordinator: Koichi Yuki, MD
• Email: koichi.yuki@childrens.harvard.edu
• Phone: 617-355-6225

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Multicenter group study of sepsis and ARDS in China

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• Non-invasive hemodynamic guidance for sepsis care on medical wards

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  Recruiting at 2 sites Regione del Veneto - AULSS n. 7 Pedemontana · Pisa, Pisa and 1 other locations · NCT07863323

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.