Examining metabolism in children with CNS tumors before and after treatment
Official title: Whole Body Metabolism in Children Before and After Treatment of CNS Tumor
Run by Copenhagen University Hospital, Rigshospitalet · NCT06380387 · Data updated 2026-11-12
This study is testing how metabolism changes in children with brain tumors before and after treatment compared to kids who have finished treatment and healthy kids.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 6 Years to 18 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Copenhagen University Hospital, Rigshospitalet Academic / other |
| Locations | 1 site (Copenhagen, Copenhagen Ø) |
| Status | Recruiting |
| Started | March 23, 2023 |
| Main results expected | December 2025 |
| Study ends | December 2026 |
| Registry record updated | April 23, 2024 |
| Trial ID | NCT06380387 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include children aged 6-18 years with newly diagnosed CNS tumors or those who have recently completed treatment.
✕Probably not a fit
Patients with competing conditions that may compromise study results or those unable to cooperate with the study procedures may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to investigate the metabolic changes in children diagnosed with CNS tumors by comparing them to children who have completed treatment and healthy controls. The research will involve a two-day assessment where participants will undergo DXA scans and complete quality of life questionnaires. The study will include three groups: children with newly diagnosed CNS tumors, those who have finished treatment, and healthy controls aged 6-18 years. The goal is to understand the hormonal and metabolic responses during and after treatment for CNS tumors.
Why it matters
Potential benefit: If successful, this study could help identify metabolic risks in children with CNS tumors, leading to better management and prevention strategies.
How similar studies have gone: While similar studies have explored metabolic changes in pediatric oncology, this specific approach comparing newly diagnosed and treated children with healthy controls is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient group A: Children with newly diagnosed CNS tumor, included just before the start of treatment or right after possible surgery. * Patient group B: Children who have completed treatment for a CNS tumor within the last month. * Healthy controls: Children admitted to the EMU because of either * Suspected convulsions * Nocturnal EEG changes * 6-18 years * Signed informed consent to participation in the trial. Exclusion Criteria: * Inability to understand the purpose of the trial or cooperate in the conduction of the experiments. For the children this will concern of course the parents or the guardians of the child. * Competing conditions at risk of compromising the results of the study. * Participation in other trials that may interfere with the results. * Intake of medications that may interfere with the results, evaluated by investigator. * Pregnancy or breastfeeding.
Where it's running
-
Department of Pediatrics and Adolescent Medicine and Copenhagen Neuromuscular Center, Rigshospitalet
Copenhagen, Copenhagen Ø, Denmark Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.