Clinical trial Recruiting at 1 site Observational Ages 18 and up

Examining lymphatic damage in brain venous thrombosis using MRI

Official title: Description of Lymphatic Damage in Encephalic Venous Thrombosis and Strictures in MRI a Reverse-recovery Sequence: a Pilot Study

Run by Fondation Ophtalmologique Adolphe de Rothschild · NCT05041569 · Data updated 2026-11-12

This study is testing how brain venous thrombosis affects lymphatic damage using MRI scans in patients to see what changes occur over time.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorFondation Ophtalmologique Adolphe de Rothschild
Research network
Locations1 site (Paris, Paris)
StatusRecruiting
StartedDecember 17, 2021
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedFebruary 18, 2026
Trial IDNCT05041569 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old who require an MRI due to suspected venous sinus pathology.

Probably not a fit

Patients with absolute contraindications to MRI or those under legal protection measures may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to describe local modifications of lymph nodes or bundles in patients undergoing MRI examinations for suspected venous thrombosis or related conditions. Participants will receive various MRI sequences, including contrast-enhanced imaging, to assess lymphatic damage and monitor potential complications. Clinical information will be collected from medical files at inclusion, discharge, and follow-up to evaluate the impact of the findings over time.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of lymphatic damage in patients with venous thrombosis, leading to improved diagnostic and treatment strategies.

How similar studies have gone: While this approach is relatively novel, similar studies have explored MRI techniques for vascular conditions, indicating potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients over 18 years of age
* Performing an MRI injected as part of care for one of the following reasons:
* suspicion of pathology likely to be associated with narrowing or obstruction of one or more venous sinuses (cerebral thrombophlebitis, tissue damage with venous extension, idiopathic HIC
* venous narrowing or obstruction proven by one of the above pathologies, requiring as part of routine care an injected MRI (search for impact, monitoring, pre-therapeutic assessment or prognosis)
* Express consent to participate in the study
* Affiliate or beneficiary of a social security scheme

Exclusion Criteria:

* Absolute contraindication to MRI
* Patient benefiting from a legal protection measure
* Pregnant or breastfeeding woman

Where it's running

  • Hhopital fondation adolphe de rothschild
    Paris, Paris, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.