Examining lymphatic damage in brain venous thrombosis using MRI
Description of Lymphatic Damage in Encephalic Venous Thrombosis and Strictures in MRI a Reverse-recovery Sequence: a Pilot Study
Fondation Ophtalmologique Adolphe de Rothschild · NCT05041569
This study is testing how brain venous thrombosis affects lymphatic damage using MRI scans in patients to see what changes occur over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild (network) |
| Locations | 1 site (Paris, Paris) |
| Trial ID | NCT05041569 on ClinicalTrials.gov |
What this trial studies
This observational study aims to describe local modifications of lymph nodes or bundles in patients undergoing MRI examinations for suspected venous thrombosis or related conditions. Participants will receive various MRI sequences, including contrast-enhanced imaging, to assess lymphatic damage and monitor potential complications. Clinical information will be collected from medical files at inclusion, discharge, and follow-up to evaluate the impact of the findings over time.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old who require an MRI due to suspected venous sinus pathology.
Not a fit: Patients with absolute contraindications to MRI or those under legal protection measures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of lymphatic damage in patients with venous thrombosis, leading to improved diagnostic and treatment strategies.
How similar studies have performed: While this approach is relatively novel, similar studies have explored MRI techniques for vascular conditions, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 18 years of age * Performing an MRI injected as part of care for one of the following reasons: * suspicion of pathology likely to be associated with narrowing or obstruction of one or more venous sinuses (cerebral thrombophlebitis, tissue damage with venous extension, idiopathic HIC * venous narrowing or obstruction proven by one of the above pathologies, requiring as part of routine care an injected MRI (search for impact, monitoring, pre-therapeutic assessment or prognosis) * Express consent to participate in the study * Affiliate or beneficiary of a social security scheme Exclusion Criteria: * Absolute contraindication to MRI * Patient benefiting from a legal protection measure * Pregnant or breastfeeding woman
Where this trial is running
Paris, Paris
- Hhopital fondation adolphe de rothschild — Paris, Paris, France (RECRUITING)
Study contacts
- Study coordinator: amélie YAVCHITZ
- Email: ayavchitz@for.paris
- Phone: 0148036454
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Description of Local Modifications of Lymph Nodes or Bundles With the FABIR Sequence in MRI