Examining lymphatic damage in brain venous thrombosis using MRI
Official title: Description of Lymphatic Damage in Encephalic Venous Thrombosis and Strictures in MRI a Reverse-recovery Sequence: a Pilot Study
Run by Fondation Ophtalmologique Adolphe de Rothschild · NCT05041569 · Data updated 2026-11-12
This study is testing how brain venous thrombosis affects lymphatic damage using MRI scans in patients to see what changes occur over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild Research network |
| Locations | 1 site (Paris, Paris) |
| Status | Recruiting |
| Started | December 17, 2021 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | February 18, 2026 |
| Trial ID | NCT05041569 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old who require an MRI due to suspected venous sinus pathology.
✕Probably not a fit
Patients with absolute contraindications to MRI or those under legal protection measures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to describe local modifications of lymph nodes or bundles in patients undergoing MRI examinations for suspected venous thrombosis or related conditions. Participants will receive various MRI sequences, including contrast-enhanced imaging, to assess lymphatic damage and monitor potential complications. Clinical information will be collected from medical files at inclusion, discharge, and follow-up to evaluate the impact of the findings over time.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of lymphatic damage in patients with venous thrombosis, leading to improved diagnostic and treatment strategies.
How similar studies have gone: While this approach is relatively novel, similar studies have explored MRI techniques for vascular conditions, indicating potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 18 years of age * Performing an MRI injected as part of care for one of the following reasons: * suspicion of pathology likely to be associated with narrowing or obstruction of one or more venous sinuses (cerebral thrombophlebitis, tissue damage with venous extension, idiopathic HIC * venous narrowing or obstruction proven by one of the above pathologies, requiring as part of routine care an injected MRI (search for impact, monitoring, pre-therapeutic assessment or prognosis) * Express consent to participate in the study * Affiliate or beneficiary of a social security scheme Exclusion Criteria: * Absolute contraindication to MRI * Patient benefiting from a legal protection measure * Pregnant or breastfeeding woman
Where it's running
-
Hhopital fondation adolphe de rothschild
Paris, Paris, France Recruiting
Study contacts
- Study coordinator: amélie YAVCHITZ
- Email: ayavchitz@for.paris
- Phone: 0148036454
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.