Examining liver cysts in patients with echinococcosis
Presentation of Protoscolexes and Acephalocysts in the Fibrous Capsule Area of the Liver With Echinococcosis During Organ-preserving Surgery
This study is trying to see if there are any germs from echinococcosis in the liver tissue near hydatid cysts in patients who need surgery for this condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov Academic / other |
| Locations | 1 site (Tashkent, Uzbekistan) |
| Trial ID | NCT06316154 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the presence of germinal elements of echinococcosis within the liver parenchyma adjacent to the fibrous capsule of hydatid cysts. Patients with primary or recurrent liver echinococcosis requiring surgical intervention will undergo echinococcectomy, during which samples of the fibrous capsule and possibly adjacent liver tissue will be collected for analysis. The study seeks to enhance understanding of the disease's pathology and improve surgical outcomes.
Who should consider this trial
Good fit: Ideal candidates are patients with liver echinococcosis cysts larger than 5 cm requiring surgical treatment.
Not a fit: Patients with cysts smaller than 5 cm or those with severe concomitant disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better surgical techniques and improved management of liver echinococcosis.
How similar studies have performed: While similar studies have explored echinococcosis, this specific observational approach focusing on germinal elements in the liver is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Presence of primary or recurrent liver echinococcosis disease requiring surgical treatment * Cyst diametr \>5 cm; * Performing one of the surgical treatment of liver echinococcosis with intraoperative sampling of part of the fibrous capsule with or without adjacent liver tissue for research; * Signed informed consent of patients for inclusion in the study; Exclusion Criteria: * Liver echinococcosis with cysts less than 5 cm in diametr; * Presence of severe concomitant disorders
Where this trial is running
Tashkent, Uzbekistan
- Republican specialized scientific and practical medical center of surgery named after academician V.Vakhidov — Tashkent, Uzbekistan, Uzbekistan (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.