Examining inter-limb asymmetry in distance runners and non-runners
Official title: Lower Limb Functional Asymmetry in Healthy Novice, Moderately and Highly-trained Distance Runners Versus Non-athletes
Run by Vrije Universiteit Brussel · NCT06808399 · Data updated 2026-11-12
This study looks at how differences between the left and right sides of the body in runners and non-runners might affect their running performance and risk of injuries.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 50 Years |
| Sex | All |
| Enrollment | 72 (estimated) |
| Sponsor | Vrije Universiteit Brussel Academic / other |
| Locations | 1 site (Ixelles-Elsene, Brussels Capital) |
| Status | Recruiting |
| Started | January 1, 2023 |
| Main results expected | June 1, 2025 |
| Study ends | June 1, 2025 |
| Registry record updated | February 5, 2025 |
| Trial ID | NCT06808399 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include distance runners aged 20 to 50 years, whether highly trained, moderately trained, or novice, as well as non-athletes who meet specific activity criteria.
✕Probably not a fit
Patients with known medical conditions affecting their physical capabilities or those outside the age range of 20 to 50 years may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the degree of inter-limb asymmetry in distance runners compared to non-runners. It aims to understand how functional asymmetries may relate to running performance and the risk of running-related injuries. Participants will include highly trained, moderately trained, novice runners, and a control group of non-athletes, all aged between 20 and 50 years. The study will assess the prevalence of asymmetry and its potential implications for injury risk and performance.
Why it matters
Potential benefit: If successful, this study could help identify risk factors for injuries in runners, leading to improved training and injury prevention strategies.
How similar studies have gone: While research on inter-limb asymmetry in athletes is limited, similar studies have indicated a correlation between asymmetry and injury risk, suggesting potential relevance for this investigation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Being aged between 20 and 50 years at Tfamiliarization * Being free from any medical attention injury (i.e., injury that results in a participant receiving medical attention) for at least 6 months upon Tfamiliarization * Speaking Dutch, French or English * Highly trained distance runners: * Running at least 150km per month for at least 3 months Moderately-trained runners: * Running between 40 - 150 km per month for at least 6 months \- Novice distance runners: * Running not more than 10km per week for the past 12 months \- Control group of non-athletes * Performing \<75min of systematic moderate to vigorous-intensity physical activity per week and having no experience in systematic (un)structured running activities for the past 5 years Exclusion Criteria: * • Being younger than 20 years or older than 50 years at Tfamiliarization * Any known relevant medical history or current condition (e.g., neurological diseases, inner ear diseases) that could affect the performance of the functional tests (e.g., balance in repeated hop tests) * Participants that have undergone a surgery at lower limb level during the past 6 months * Medication or drug use (e.g., blood pressure medicines)that could affect the performance of the functional tests (e.g., balance in repeated hop tests) * Participants performing more than two hours per week of unilateral sports (e.g., tennis or soccer)
Where it's running
-
MOVE Research group
Ixelles-Elsene, Brussels Capital, Belgium Recruiting
Study contacts
- Study coordinator: Joachim D'Hondt
- Email: Joachim.dhondt@vub.be
- Phone: +32 (0) 629 27 35
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Training to reduce oxidative stress in knee OA
A six-week program compares supervised knee-strengthening training with a daily 6,000-step walking plan to see if it improves pain, function, and blood markers of cellular stress in people with knee osteoarthritis.
-
Cognitive Model for Behavioral Interventions to reduce behavioral and psychological symptoms in people with dementia
This project will try a person-centered, non-drug program called CoMBI to see if it reduces behavioral and psychological symptoms in people with dementia living in nursing homes and eases caregiver burden.
-
Using wearable sensors to monitor mental fatigue and its effect on running performance
This project will test whether wearable sensors can detect mental fatigue in healthy trained runners (18–35) and predict how that fatigue affects a 5-km treadmill time trial.
-
Tackling Muscle Loss in Hospitalized Older Adults with Blood Flow Restriction and a Gamified Muscle Check
In this study, older adults who are in the hospital and at risk of losing muscle strength will try a light, safe exercise program paired with blood flow restriction and driven by a tablet game to see if it preserves strength during hospitalization.
-
Gait data collection using wearable sensors and motion capture to test gait events
This study tests how well wearable IMU sensors can detect gait events by comparing them to gold-standard motion capture in healthy adults.
-
Mild brain stimulation added to exercise for chronic widespread pain
This study will test whether adding mild brain stimulation (tDCS) during a short bout of aerobic exercise helps people with chronic widespread pain have less pain and fatigue afterward.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.