Examining inter-limb asymmetry in distance runners and non-runners

Lower Limb Functional Asymmetry in Healthy Novice, Moderately and Highly-trained Distance Runners Versus Non-athletes

Observational Vrije Universiteit Brussel · NCT06808399

This study looks at how differences between the left and right sides of the body in runners and non-runners might affect their running performance and risk of injuries.

Quick facts

Study typeObservational
Enrollment72 (estimated)
Ages20 Years to 50 Years
SexAll
SponsorVrije Universiteit Brussel Academic / other
Locations1 site (Ixelles-Elsene, Brussels Capital)
Trial IDNCT06808399 on ClinicalTrials.gov

What this trial studies

This observational study investigates the degree of inter-limb asymmetry in distance runners compared to non-runners. It aims to understand how functional asymmetries may relate to running performance and the risk of running-related injuries. Participants will include highly trained, moderately trained, novice runners, and a control group of non-athletes, all aged between 20 and 50 years. The study will assess the prevalence of asymmetry and its potential implications for injury risk and performance.

Who should consider this trial

Good fit: Ideal candidates include distance runners aged 20 to 50 years, whether highly trained, moderately trained, or novice, as well as non-athletes who meet specific activity criteria.

Not a fit: Patients with known medical conditions affecting their physical capabilities or those outside the age range of 20 to 50 years may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify risk factors for injuries in runners, leading to improved training and injury prevention strategies.

How similar studies have performed: While research on inter-limb asymmetry in athletes is limited, similar studies have indicated a correlation between asymmetry and injury risk, suggesting potential relevance for this investigation.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Being aged between 20 and 50 years at Tfamiliarization

  * Being free from any medical attention injury (i.e., injury that results in a participant receiving medical attention) for at least 6 months upon Tfamiliarization
  * Speaking Dutch, French or English
* Highly trained distance runners:

  * Running at least 150km per month for at least 3 months

Moderately-trained runners:

* Running between 40 - 150 km per month for at least 6 months

  \- Novice distance runners:
* Running not more than 10km per week for the past 12 months

  \- Control group of non-athletes
* Performing \<75min of systematic moderate to vigorous-intensity physical activity per week and having no experience in systematic (un)structured running activities for the past 5 years

Exclusion Criteria:

* • Being younger than 20 years or older than 50 years at Tfamiliarization

  * Any known relevant medical history or current condition (e.g., neurological diseases, inner ear diseases) that could affect the performance of the functional tests (e.g., balance in repeated hop tests)
  * Participants that have undergone a surgery at lower limb level during the past 6 months
  * Medication or drug use (e.g., blood pressure medicines)that could affect the performance of the functional tests (e.g., balance in repeated hop tests)
  * Participants performing more than two hours per week of unilateral sports (e.g., tennis or soccer)

Where this trial is running

Ixelles-Elsene, Brussels Capital

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Healthy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.