Examining IDH1 and OCT4 markers in patients with high grade astrocytoma
IDH1 and OCT4 Markers as a Prognostic Factor in Clinical Outcome of High Grade Astrocytic Glioma
This study is trying to see if certain markers in the brain tumor can help predict how well patients with high grade astrocytoma will do after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 35 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut) |
| Trial ID | NCT06214689 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between IDH1 and OCT4 biomarkers and the prognosis of patients with high grade astrocytoma following surgical excision. It aims to analyze how these biomarkers correlate with progression-free survival and overall survival in both prospective and retrospective patient samples. By understanding these relationships, the study seeks to provide insights into the prognostic value of these markers in clinical practice.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with high grade astrocytic glioma who are fit for surgical intervention.
Not a fit: Patients with low grade gliomas or those unfit for surgery are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance prognostic assessments for patients with high grade astrocytoma, leading to more personalized treatment approaches.
How similar studies have performed: While the specific biomarkers IDH1 and OCT4 have been studied in various contexts, the exact approach of this observational study is relatively novel and untested in high grade astrocytoma.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients of high grade astrocytic glioma patients fit for surgery Exclusion Criteria: * patients of low grade glioma patients unfit for surgery
Where this trial is running
Asyut
- Faculty of Medicine of Assiut University — Asyut, Egypt (Recruiting)
Study contacts
- Study coordinator: Abdelrahman A Salama, resident
- Email: adhamsalama001@gmail.com
- Phone: 01002796190
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.