Clinical trial Recruiting at 1 site Observational Ages 18 to 50 Men only

Examining how tucking affects semen quality in trans women

Official title: The Effect of Tucking on Semen Quality of Adult Trans Women Compared to Semen Quality of Trans Women Who do Not Tuck - a Case Control Study

Run by Medical University Innsbruck · NCT06530992 · Data updated 2026-11-12

This study is testing how tucking affects sperm quality in trans women who want to preserve their fertility before starting hormone therapy.

Quick facts

Study typeObservational
Ages18 Years to 50 Years
SexMen only
Enrollment40 (estimated)
SponsorMedical University Innsbruck
Academic / other
Locations1 site (Innsbruck)
StatusRecruiting
StartedJuly 17, 2024
Main results expectedJuly 2029
Study endsDecember 2029
Registry record updatedJuly 31, 2024
Trial IDNCT06530992 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are female transgender individuals aged 18 to 50 who are preparing to start gender-affirming hormone therapy.

Probably not a fit

Patients who are undergoing ongoing gender-affirming genital surgery or have conditions like hypogonadism or diabetes may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the impact of tucking on semen quality in adult trans women, particularly in the context of fertility preservation prior to starting gender-affirming hormone therapy (GAHT). It aims to analyze the effects of tucking, a method used to minimize crotch bulge, on sperm concentration and motility. The study will involve female transgender patients aged 18 to 50 who are eligible for GAHT and will assess their semen quality before and during the practice of tucking. The findings could provide valuable insights into fertility issues faced by trans women.

Why it matters

Potential benefit: If successful, this study could help inform trans women about the effects of tucking on their fertility and guide them in making decisions about fertility preservation.

How similar studies have gone: While there have been studies on semen quality in trans women, the specific focus on tucking and its effects on fertility is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Female transgender patients between the ages of 18 to 50 years of age who are seen at the University Clinic for Gyn. Endocrinology and Reproductive Medicine of the Medical University of Innsbruck. Patients must have met the eligibility and readiness criteria for gender-affirming hormone therapy

Exclusion Criteria:

* Ongoing GAHT gender affirming genital surgery Hypogonadism Diabetes mellitus Cystic Fibrosis Varicocele Cryptorchism Post-sterilization Incapacity to consent

Where it's running

  • University clinic for Gynecological Endocrinology and Reproductive Medicine Department of Gynecology Medical University of Innsbruck
    Innsbruck, Austria
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.