Examining how tucking affects semen quality in trans women

The Effect of Tucking on Semen Quality of Adult Trans Women Compared to Semen Quality of Trans Women Who do Not Tuck - a Case Control Study

Observational Medical University Innsbruck · NCT06530992

This study is testing how tucking affects sperm quality in trans women who want to preserve their fertility before starting hormone therapy.

Quick facts

Study typeObservational
Enrollment40 (estimated)
Ages18 Years to 50 Years
SexMale
SponsorMedical University Innsbruck Academic / other
Locations1 site (Innsbruck)
Trial IDNCT06530992 on ClinicalTrials.gov

What this trial studies

This observational study investigates the impact of tucking on semen quality in adult trans women, particularly in the context of fertility preservation prior to starting gender-affirming hormone therapy (GAHT). It aims to analyze the effects of tucking, a method used to minimize crotch bulge, on sperm concentration and motility. The study will involve female transgender patients aged 18 to 50 who are eligible for GAHT and will assess their semen quality before and during the practice of tucking. The findings could provide valuable insights into fertility issues faced by trans women.

Who should consider this trial

Good fit: Ideal candidates for this study are female transgender individuals aged 18 to 50 who are preparing to start gender-affirming hormone therapy.

Not a fit: Patients who are undergoing ongoing gender-affirming genital surgery or have conditions like hypogonadism or diabetes may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help inform trans women about the effects of tucking on their fertility and guide them in making decisions about fertility preservation.

How similar studies have performed: While there have been studies on semen quality in trans women, the specific focus on tucking and its effects on fertility is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Female transgender patients between the ages of 18 to 50 years of age who are seen at the University Clinic for Gyn. Endocrinology and Reproductive Medicine of the Medical University of Innsbruck. Patients must have met the eligibility and readiness criteria for gender-affirming hormone therapy

Exclusion Criteria:

* Ongoing GAHT gender affirming genital surgery Hypogonadism Diabetes mellitus Cystic Fibrosis Varicocele Cryptorchism Post-sterilization Incapacity to consent

Where this trial is running

Innsbruck

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions TransgenderGender IncongruenceFertility Issues
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.