Examining how the menstrual cycle affects exercise performance
Official title: The Impact of the Menstrual Cycle on Physical Exercise and Performance
Run by Karolinska Institutet · NCT05697263 · Data updated 2026-11-12
This study tests how different phases of the menstrual cycle affect exercise performance in women who train hard to see if adjusting workouts can improve their fitness and reduce symptoms.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 35 Years |
| Sex | Women only |
| Enrollment | 111 (estimated) |
| Sponsor | Karolinska Institutet Academic / other |
| Locations | 1 site (Stockholm) |
| Status | Recruiting |
| Started | August 1, 2023 |
| Main results expected | July 2027 |
| Study ends | July 2027 |
| Registry record updated | August 13, 2026 |
| Trial ID | NCT05697263 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women who exercise at least 3-4 times a week, have a regular menstrual cycle of 26-32 days, and are in good health.
✕Probably not a fit
Patients using hormonal contraceptives, those on regular medication, or with chronic diseases or recent injuries may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the impact of the menstrual cycle on physical exercise and athletic performance among women who regularly engage in high-level training. It aims to evaluate how periodizing exercise according to different phases of the menstrual cycle influences aerobic fitness, premenstrual symptoms, body composition, and muscle-related factors. The study employs a randomized, controlled design to ensure robust methodology and reliable results, addressing gaps in previous research on this topic.
Why it matters
Potential benefit: If successful, this study could provide tailored exercise recommendations for women, enhancing their athletic performance and overall health.
How similar studies have gone: While there have been underpowered studies on this topic, this study aims to provide a more rigorous evaluation, making it a novel approach in the field.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women exercising at least 3-4 times a week on a high level * Regular menstrual cycle with 26-32 cycle days. * Fully healthy and be able to follow the training program. Exclusion Criteria: * Hormonal contraceptive users, * Users of regular medication * Chronic disease * Past or present neurological disorder * Recent musculoskeletal injury
Where it's running
-
Angelica Lindén Hirschberg
Stockholm, Sweden Recruiting
Study contacts
- Study coordinator: Angelica L Hirschberg, Med dr
- Email: angelica.hirschberg.linden@ki.se
- Phone: +46702559924
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.