Examining how spinal manipulation affects motor control in adolescents with scoliosis
Study on the Central Motor Regulation Mechanism in Adolescent Idiopathic Scoliosis (AIS) Patients Based on HD-sEMG, EEG, and Neuromuscular Coupling Analysis
The First Affiliated Hospital of Zhejiang Chinese Medical University · NCT06758115
This study is testing how spinal manipulation affects movement control in teenagers with scoliosis to see if it helps them improve their balance and muscle function.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 10 Years to 18 Years |
| Sex | All |
| Sponsor | The First Affiliated Hospital of Zhejiang Chinese Medical University (other) |
| Locations | 1 site (Hangzhou) |
| Trial ID | NCT06758115 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the effects of spinal manipulation on motor control in patients with Adolescent Idiopathic Scoliosis (AIS). It involves both outpatient and inpatient participants who receive standardized spinal manipulation treatment. The efficacy of this treatment is evaluated using clinical outcome measures, high-density electromyography (HD-EMG) for assessing paraspinal muscle function, and the Pro-Kin balance system for analyzing trunk stability. Additionally, the study employs high-density sEMG-EEG technology to analyze the central motor network's response to treatment, focusing on the synchronization between brain and muscle electrical signals.
Who should consider this trial
Good fit: Ideal candidates are adolescents aged 10 years and older with a Cobb angle between 10° and 40° and no prior treatment for scoliosis.
Not a fit: Patients with severe primary diseases or those who have previously received treatments that may affect the study's outcomes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance treatment strategies for improving motor control in adolescents with scoliosis.
How similar studies have performed: While the approach of using spinal manipulation in AIS is explored, the specific combination of methodologies in this study is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients aged ≥10 years; 2. Risser sign grade 0-3; 3. Cobb angle between 10° and 40°; 4. No prior treatment; 5. Female patients within 1 year after menarche or before menstruation; 6. The patient's guardian signs the informed consent form for treatment. Exclusion Criteria: 1. Those who do not meet the diagnostic criteria for AIS or inclusion criteria; 2. Patients with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney, and hematopoietic system disorders, or those with mental illnesses; 3. Patients with thrombocytopenia, coagulation disorders, or a tendency to bleed; 4. Patients who are afraid of the treatment and cannot tolerate it; 5. Those who have already received other treatments that may affect the study's outcome measures.
Where this trial is running
Hangzhou
- the First Affiliated Hospital of Zhejiang Chinese Medical University — Hangzhou, China (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Adolescent Idiopathic Scoliosis