Examining how spinal manipulation affects motor control in adolescents with scoliosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the effects of spinal manipulation on motor control in patients with Adolescent Idiopathic Scoliosis (AIS). It involves both outpatient and inpatient participants who receive standardized spinal manipulation treatment. The efficacy of this treatment is evaluated using clinical outcome measures, high-density electromyography (HD-EMG) for assessing paraspinal muscle function, and the Pro-Kin balance system for analyzing trunk stability. Additionally, the study employs high-density sEMG-EEG technology to analyze the central motor network's response to treatment, focusing on the synchronization between brain and muscle electrical signals.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients aged ≥10 years;
2. Risser sign grade 0-3;
3. Cobb angle between 10° and 40°;
4. No prior treatment;
5. Female patients within 1 year after menarche or before menstruation;
6. The patient's guardian signs the informed consent form for treatment.

Exclusion Criteria:

1. Those who do not meet the diagnostic criteria for AIS or inclusion criteria;
2. Patients with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney, and hematopoietic system disorders, or those with mental illnesses;
3. Patients with thrombocytopenia, coagulation disorders, or a tendency to bleed;
4. Patients who are afraid of the treatment and cannot tolerate it;
5. Those who have already received other treatments that may affect the study's outcome measures.

Where it's running

• the First Affiliated Hospital of Zhejiang Chinese Medical University
  Hangzhou, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.