Examining how pregnancy factors affect the risk of type 1 diabetes in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the impact of prenatal and obstetric maternal exposures on the risk of type 1 diabetes and islet autoimmunity in children. It focuses on pregnant women who have type 1 diabetes or a first-degree relative with the condition, enrolling both mothers and biological fathers to assess genetic and health contributions. Participants will complete three visits during pregnancy to gather data on various exposures and their potential effects on the child's health. The study aims to recruit a total of 2,000 participants across multiple renowned medical centers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pregnant women and their offspring where the offspring has a first degree relative (mother, biological father, full sibling) with type 1 diabetes
* Mother is 18 or older
* Mother is both gestational and biological mother
* Gestation up to 24 weeks at enrollment

Exclusion Criteria:

* Parents do not agree to inclusion of the offspring in the study and genetic risk testing
* Greater than singleton pregnancy

Where it's running

• University of Colorado
  Aurora, Colorado, United States Recruiting
• Joslin Diabetes Center
  Boston, Massachusetts, United States Recruiting
• Mt Sinai
  New York, New York, United States Recruiting
• Ohio State University
  Columbus, Ohio, United States Not yet recruiting

Study contacts

• Principal investigator: JANET K SNELL-BERGEON, PhD, MPH — University of Colorado, Denver
• Study coordinator: JANET K SNELL-BERGEON, PhD, MPH
• Email: Janet.Snell-Bergeon@cuanschutz.edu
• Phone: 7208917122

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.