Examining how physical activity and hormones affect metabolism in women

Effects of the Interaction Between Physical Activity Level and Hormonal Status on Energy Metabolism and Nutritional Responses in Women

University Hospital, Clermont-Ferrand · NCT05944653

This study looks at how exercise and hormones affect metabolism in women aged 18 to 44 with a normal weight to see if it can help improve their health before menopause.

Quick facts

Study typeObservational
Enrollment48 (estimated)
Ages18 Years to 44 Years
SexFemale
SponsorUniversity Hospital, Clermont-Ferrand (other)
Locations1 site (Clermont-Ferrand)
Trial IDNCT05944653 on ClinicalTrials.gov

What this trial studies

This observational study investigates the relationship between physical activity levels, hormonal status, and energy metabolism in women aged 18 to 44 with a normal BMI. It aims to address the cardiometabolic risks associated with obesity in women of childbearing age, a demographic often overlooked in research. By focusing on the natural hormonal variations throughout the menstrual cycle, the study seeks to provide insights into how these factors influence nutritional responses and overall health. The findings could help inform better health strategies for women before menopause.

Who should consider this trial

Good fit: Ideal candidates for this study are women aged 18 to 44 with a BMI between 18 and 25 who are not pregnant or lactating.

Not a fit: Patients with irregular menstrual cycles, those undergoing weight loss, or women who are perimenopausal or postmenopausal may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved health strategies for women, potentially reducing obesity-related health risks.

How similar studies have performed: While there is limited research specifically targeting this demographic, studies on hormonal influences on metabolism have shown promising results, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged between 18 and 44y
* BMI between 18 and 25 kg.m-2
* Subject able to provide informed consent to participate
* Subject with a Social Security

Exclusion Criteria:

* Medical or surgical history judged by the investigator to be incompatible with the study
* Presence of comorbidities or pathology that could interfere with the study data
* Women in the process of food restriction or weight loss at the time of inclusion or during the last three months
* Irregular menstrual cycles
* Menstrual cycles \< 25 days or greater than 35 days
* Pregnant or lactating women
* Per or post menopausal women
* Claustrophobia
* Person in period of exclusion from another study
* Person under guardianship or safeguard of justice; or subject without social security

Where this trial is running

Clermont-Ferrand

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Women, Metabolism

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.