Examining how mothers pass COVID-19 antibodies to their infants

Children's Hospital of Chongqing Medical University

Children's Hospital of Chongqing Medical University · NCT05851911

This study looks at how mothers pass COVID-19 antibodies to their babies under 2 years old to see if it helps protect them from getting sick.

Quick facts

Study typeObservational
Enrollment300 (estimated)
Ages0 Months to 2 Years
SexAll
SponsorChildren's Hospital of Chongqing Medical University (other)
Drugs / interventionschemotherapy
Locations1 site (Chongqing, Chongqing)
Trial IDNCT05851911 on ClinicalTrials.gov

What this trial studies

This observational study investigates the transmission of COVID-19 antibodies from mothers to their infants, focusing on children aged 0-2. By monitoring the specific antibodies present in young children, the study aims to understand the effectiveness of maternal passive immunity and its implications for children's risk of COVID-19 infection. The findings will contribute to developing immune prevention strategies for this vulnerable population.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 0-2 who have not undergone blood transfusions or immunosuppressive therapies.

Not a fit: Patients who may not benefit from this study include those with a history of blood transfusions, chemotherapy, or immune system-related diseases.

Why it matters

Potential benefit: If successful, this study could enhance understanding of maternal immunity and improve strategies for protecting infants from COVID-19.

How similar studies have performed: While there is limited research specifically on maternal transmission of COVID-19 antibodies, similar studies on maternal antibody transfer for other infections have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Children aged 0-2;
2. No history of blood transfusion, chemotherapy, or related immunosuppressive therapy; No immune system related diseases;

Exclusion Criteria:

Not willing to participate

Where this trial is running

Chongqing, Chongqing

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Passive Transmission of Maternal and Infant Antibodies

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.