Examining how Hb F levels relate to the severity of beta thalassemia
Association of Hb F Level With Clinical Severity of Beta Thalassemia
This study looks at how levels of a specific type of hemoglobin (Hb F) affect the severity of beta thalassemia in patients to help improve treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1200 (estimated) |
| Sex | All |
| Sponsor | Nanfang Hospital, Southern Medical University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT04917978 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the relationship between Hb F levels and the clinical severity of beta thalassemia in diagnosed patients. By analyzing hematological phenotypes, the study seeks to understand how variations in Hb F production can influence the phenotypic diversity observed in beta thalassemia patients. The findings could provide insights into the management and treatment of this condition based on individual Hb F levels.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with beta thalassemia.
Not a fit: Patients with iron deficiency anemia will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved personalized treatment strategies for patients with beta thalassemia based on their Hb F levels.
How similar studies have performed: While this approach is focused on Hb F levels, similar studies have shown promising results in understanding the genetic and phenotypic diversity in beta thalassemia.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosed with beta-thalassemia Exclusion Criteria: * Iron Deficiency Anemia
Where this trial is running
Guangzhou, Guangdong
- Southern Medical University — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Study coordinator: Xiangmin Xu, Prof. Dr.
- Email: xixm@smu.edu.cn
- Phone: 02061648293
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.