Clinical trial Recruiting at 1 site Observational Ages 0 to 1 Year

Examining how gut bacteria and vitamin D affect allergic diseases in infants

Official title: The Roles of Human Microbiome and Vitamin D in the Development of Childhood Allergic Diseases

Run by China Medical University Hospital · NCT05670262 · Data updated 2026-11-12

This study is trying to see how gut bacteria and vitamin D levels affect the chances of infants developing allergic diseases like asthma and eczema in their first year of life.

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Quick facts

Study typeObservational
Ages0 Years to 1 Year
SexAll
Enrollment6000 (estimated)
SponsorChina Medical University Hospital
Academic / other
Locations1 site (Taichung)
StatusRecruiting
StartedAugust 4, 2022
Main results expectedJuly 31, 2027
Study endsJuly 31, 2027
Registry record updatedFebruary 7, 2024
Trial IDNCT05670262 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are term newborn babies born at China Medical University Hospital.

Probably not a fit

Patients who are premature, have congenital anomalies, or require immediate resuscitation after birth may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational birth cohort study aims to evaluate the influence of the human microbiome and vitamin D on the development of allergic diseases in infants under one year of age. It focuses on understanding how genetic and environmental factors, particularly early exposure to allergens and microbes, contribute to conditions like atopic dermatitis, allergic rhinitis, and asthma. The study will assess the relationship between vitamin D levels, vitamin D binding protein, and gut microbiota colonization in newborns. By analyzing these factors, the researchers hope to uncover the mechanisms behind the increasing prevalence of allergic diseases in young children.

Why it matters

Potential benefit: If successful, this study could lead to improved strategies for preventing allergic diseases in infants.

How similar studies have gone: While the role of the microbiome and vitamin D in allergic diseases has been explored, this specific birth cohort approach is relatively novel and untested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All term newborn babies who are born in China Medical University Hospital. The term baby defines the maternal gestational age between 37 0/7 weeks to 41 6/7 weeks.

Exclusion Criteria:

* The exclusion criteria are prematurity newborn, congenital anomalies and cardiopulmonary failure need for resuscitation immediately after birth.

Where it's running

  • China Medical University Hospital
    Taichung, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.