Examining how gum inflammation affects healing after tooth extraction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will recruit 25 healthy adults aged 21-70 who require the extraction of a posterior tooth. Before the extraction, various clinical markers of periodontal inflammation, body mass index, and dental radiographs will be assessed. The tooth will be extracted atraumatically, and soft tissue biopsies will be taken from the extraction site at both two weeks and three months post-operation to analyze the immune response during wound healing. The study aims to understand the relationship between periodontal inflammation and the healing process following dental procedures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* non-restorable posterior tooth (molar/premolar) in need of extraction

Exclusion Criteria:

* systemic disease that effects inflammation

Where it's running

• University of Nebraska, College of Dentistry
  Lincoln, Nebraska, United States Recruiting

Study contacts

• Study coordinator: Amy C Killeen, DDS
• Email: akilleen@unmc.edu
• Phone: 402-472-7848

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.