Examining how gadolinium contrast agents are excreted in urine after MRI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to investigate the urinary excretion kinetics of gadolinium contrast agents (Gd-CAs) used in MRI examinations. Patients who have been prescribed an MRI with Gd-CAs will provide blood and urine samples before and after the injection of the contrast agent. The goal is to assess the feasibility of recovering gadolinium from urine to prevent environmental contamination, as current wastewater treatment processes do not eliminate these compounds effectively. This research could lead to improved protocols for managing gadolinium waste in medical settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients:

* over 18 years of age
* with a prescription for MRI with gadolinium-based contrast agents (Gd-CAs) injection validated by a radiologist
* affiliated with a health insurance plan
* have signed an informed consent form

Exclusion Criteria:

* Patients:
* with known allergy to gadolinium-based contrast agents (Gd-CAs)
* with known severe renal impairment (GFR \< 30 mL/min)
* on dialysis
* with urinary incontinence
* with an ongoing urinary tract infection
* under hydric or hydrosodic restriction
* unable to urinate independently
* Protected persons (under guardianship, curatorship or safeguard of justice)
* Pregnant or breast-feeding women

Where it's running

• CHR Metz-Thionville/Hopital de Mercy
  Metz, Grand Est, France Recruiting
• CHR Metz-Thionville / Hopital Bel Air
  Thionville, France Recruiting

Study contacts

• Principal investigator: Rémi DUPRES, MD — CHR Metz Thionville Hopital Mercy
• Study coordinator: Arpiné EL NAR, PhD
• Email: projet-recherche-clinique@chr-metz-thionville.fr
• Phone: 0033387557766

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.