Examining how different feeding methods affect gut health in newborns with gastrointestinal issues

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of an exclusive human milk diet compared to standard feeding practices on feeding outcomes and gut microbiome composition in infants with congenital gastrointestinal pathologies. By focusing on conditions such as gastroschisis and Hirschsprung disease, the research aims to determine how these feeding sources influence the time to achieve full feeds. The study will enroll eligible infants and monitor their feeding progress and gut health over a specified period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Infants with gastroschisis, giant omphalocele, intestinal atresia, mid-gut volvulus, hirschsprungs disease.

Exclusion Criteria:

1. Infant has already been on feeds
2. Infants \<34 weeks gestation
3. Parents with contraindications to providing milk (i.e. drug use-cocaine, fentanyl, meth BUT oxy/suboxone/marijuana OK)
4. Complicated gastroschisis
5. Short gut syndrome
6. Additional congenital anomalies that affect ability to tolerate milk (i.e. cyanotic congenital heart disease BUT kidney disease ok)

Where it's running

• Seattle Children's Hospital
  Seattle, Washington, United States Recruiting

Study contacts

• Principal investigator: Katie Strobel, MD — Seattle Children's Hospital
• Study coordinator: Leonel Arellano
• Email: leonel.arellano@seattlechildrens.org
• Phone: 915-443-4390

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.