Examining how chronic venous obstruction affects walking and pain in patients
Assessment of the Relationship Between Severity of Chronic Venous Obstruction and Venous Claudication
This study looks at how problems with blood flow in the legs affect walking and pain in people who have had blood clots, to see if treatments can help them walk better and feel less pain.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | RWTH Aachen University Academic / other |
| Locations | 1 site (Aachen, NRW) |
| Trial ID | NCT05662761 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the relationship between the severity of chronic venous obstruction and the symptoms of venous claudication in patients. It focuses on individuals who have experienced postthrombotic syndrome following deep vein thrombosis, which can significantly impact their quality of life. By measuring walking performance and pain-free walking distance before and after venous interventions, the study seeks to identify significant changes in patient symptoms and overall walking ability. The findings could provide valuable insights into the effectiveness of endovascular procedures for improving patient outcomes.
Who should consider this trial
Good fit: Ideal candidates include patients aged 18-80 with specific obstructions in major veins such as the femoral vein or inferior vena cava.
Not a fit: Patients under 18, those unable to consent, or individuals with advanced peripheral arterial disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of how to improve walking performance and quality of life for patients with chronic venous insufficiency.
How similar studies have performed: Previous studies have shown improvements in quality of life and walking performance in similar patient populations, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients with an obstruction in the femoral vein communis, V. iliaca externa, V. iliaca communis or V. cava inferior 2. Age: 18-80 years old 3. Signed informed consent form 4. Persons who are legally competent and mentally capable, to follow the instructions of the staff Exclusion Criteria: 1. Patients under 18 years of age. 2. Patients who are unable to consent and/or not in are able to appreciate the nature, importance and scope of the study understand and give their consent in writing. 3. Persons acting by administrative or judicial order are housed in a facility 4. Patients who abuse drugs 5. Peripheral arterial disease stage IIb, III and IV -
Where this trial is running
Aachen, NRW
- Universitätsklinikum Aachen — Aachen, Nrw, Germany (Recruiting)
Study contacts
- Principal investigator: Houman Jalaie, MD — Universitätsklinikum Aachen Klinik für Gefäßchirurgie
- Study coordinator: Mohammad E Barbati, MD
- Email: mbarbati@ukaachen.de
- Phone: +492418035292
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.