Examining how chemotherapy affects daily performance and executive functions in adults with cancer

Effects of Chemotherapy on Perceived Daily Performance and Executive Functions of Adults With Cancer

Not applicable Interventional Bnai Zion Medical Center · NCT05599698

This study tests how chemotherapy affects daily activities and thinking skills in adults who have just been diagnosed with cancer.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment38 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorBnai Zion Medical Center Government
Drugs / interventionschemotherapy
Locations1 site (Haifa)
Trial IDNCT05599698 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of chemotherapy on perceived daily performance and executive functioning in adults diagnosed with non-central nervous system cancers. Participants will be newly diagnosed individuals who are about to begin chemotherapy, and the study aims to assess changes in their cognitive and daily functioning as they undergo treatment. The research will involve evaluating patients' experiences and perceptions before and after chemotherapy to understand the effects on their quality of life.

Who should consider this trial

Good fit: Ideal candidates are adults newly diagnosed with primary non-central nervous system malignancies who are about to start chemotherapy.

Not a fit: Patients with central nervous system malignancies, previous malignancies, or significant neurological conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into how chemotherapy affects cognitive functions, potentially leading to better supportive care strategies for cancer patients.

How similar studies have performed: While studies on chemotherapy's effects on cognitive function exist, this specific focus on perceived daily performance in non-central nervous system cancers is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Newly diagnosed with a primary non-central nervous system malignancy (lung, breast, colon, ulcer, urinary tract, canine tumors).
* Stages I-III.
* Pre-commencement of adjuvant (post-surgery) or neoadjuvant (prior to surgery) chemotherapy.
* Understand and read Hebrew.
* Have at least 12 years of education.

Exclusion Criteria:

* Diagnosed with central nervous system malignancies.
* Had a previous malignancy.
* Have or had metastatic disease.
* Have a history of a neurological condition or severe depression.

Where this trial is running

Haifa

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cancerexecutive functioningdaily functioningchemotherapynon-central nervous system malignancy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.