Examining how cerebellar lesions affect synchronization abilities
Understanding the Effect of Variances on Precision in Predictive Coding When Walking to Music and Metronomes in Persons With Cerrebellar Lesions
This study tests how damage to a part of the brain called the cerebellum affects people's ability to keep in time with music and their overall movement skills.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Hasselt University Academic / other |
| Locations | 1 site (Lodelinsart) |
| Trial ID | NCT04887753 on ClinicalTrials.gov |
What this trial studies
This study involves individuals with cerebellar lesions and healthy controls to assess their motor and cognitive functions. Participants will undergo a series of sessions, including a descriptive session to collect clinical data and experimental sessions to evaluate beat perception and synchronization abilities through finger tapping and walking tasks. The study will also measure brain activity using EEG, along with spatio-temporal gait parameters and subjective assessments of fatigue, motivation, and walking speed.
Who should consider this trial
Good fit: Ideal candidates include individuals diagnosed with cerebellar lesions who can walk at a speed of 0.8-1.2 m/s for six minutes.
Not a fit: Patients with cognitive impairments that hinder understanding instructions, beat amusia, deafness, or those who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of motor and cognitive impairments in patients with cerebellar lesions, potentially leading to improved therapeutic strategies.
How similar studies have performed: While there may be studies examining synchronization in motor tasks, this specific approach focusing on cerebellar lesions is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosis of cerrebellar lesions * walking speed 0.8-1.2m/s, ability to walk for 6 minutes continuously (canes and rollators are permitted) Exclusion Criteria: * cognitive impairment impeding understanding of * instructions, * beat amusia, * deafness, * pregnancy
Where this trial is running
Lodelinsart
- Hôpital Civil Marie Curie — Lodelinsart, Belgium (Recruiting)
Study contacts
- Principal investigator: Peter Feys, prof. dr. — Hasselt University
- Study coordinator: Peter Feys, prof. dr.
- Email: peter.feys@uhasselt.be
- Phone: +32 11 29 21 23
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.