Examining how body position affects bladder function tests in neurological patients

Does Position Influence the Diagnosis of Detrusor Overactivity in a Neurological Population - a Concordance Study Between Lying and Sitting Position

NA · Assistance Publique - Hôpitaux de Paris · NCT05949567

This study is testing whether changing body positions during bladder tests can help people with neurological conditions like Multiple Sclerosis and Parkinson's disease get more accurate results.

Quick facts

PhaseNA
Study typeInterventional
Enrollment160 (estimated)
Ages18 Years and up
SexAll
SponsorAssistance Publique - Hôpitaux de Paris (other)
Locations1 site (Paris, France)
Trial IDNCT05949567 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of body position on the diagnosis of detrusor overactivity during urodynamic examinations in patients with neurological disorders such as Multiple Sclerosis and Parkinson's disease. It aims to challenge existing guidelines that recommend sitting or standing positions for these tests, which may not be feasible for many neurological patients. Participants will undergo urodynamic assessments in both sitting and lying positions, with data collected and analyzed to determine the effectiveness of each position. The goal is to establish tailored recommendations for urodynamic testing in this specific patient population.

Who should consider this trial

Good fit: Ideal candidates include adults with Multiple Sclerosis or Parkinson's disease who require urodynamic assessment and have symptoms of overactive bladder.

Not a fit: Patients who do not have neurological disorders or those who oppose undergoing urodynamic examinations will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic practices for bladder dysfunction in patients with neurological conditions.

How similar studies have performed: While there is limited research specifically addressing this population, previous studies have indicated that position can influence urodynamic outcomes, suggesting potential for success in this novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient with MS or neurologically confirmed Parkinson's disease, with indication for urodynamic assessment - 1st assessment
* Clinical overactive bladder syndrome with USP overactive bladder sub-score \> or = 4 - Age ≥18 years
* In men: no prostatic hypertrophy on ultrasonography
* In women: no stress urinary incontinence (SUI); USP SUI subscore ≤ 2
* Affiliated with a social security scheme (excluding AME).
* Free and informed written consent

Exclusion Criteria:

* Opposition to the performance of a Urodynamic exam as part of treatment

Where this trial is running

Paris, France

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Urodynamic Exam, Neurologic Disorder, Urodynamic exam, detrusor overactivity, positon

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.