Examining how body position affects bladder function tests in neurological patients
Official title: Does Position Influence the Diagnosis of Detrusor Overactivity in a Neurological Population - a Concordance Study Between Lying and Sitting Position
Run by Assistance Publique - Hôpitaux de Paris · NCT05949567 · Data updated 2026-11-12
This study is testing whether changing body positions during bladder tests can help people with neurological conditions like Multiple Sclerosis and Parkinson's disease get more accurate results.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 160 (estimated) |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Paris, France) |
| Status | Recruiting |
| Started | April 2, 2024 |
| Main results expected | April 2, 2027 |
| Study ends | April 2, 2027 |
| Registry record updated | April 17, 2026 |
| Trial ID | NCT05949567 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults with Multiple Sclerosis or Parkinson's disease who require urodynamic assessment and have symptoms of overactive bladder.
✕Probably not a fit
Patients who do not have neurological disorders or those who oppose undergoing urodynamic examinations will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the impact of body position on the diagnosis of detrusor overactivity during urodynamic examinations in patients with neurological disorders such as Multiple Sclerosis and Parkinson's disease. It aims to challenge existing guidelines that recommend sitting or standing positions for these tests, which may not be feasible for many neurological patients. Participants will undergo urodynamic assessments in both sitting and lying positions, with data collected and analyzed to determine the effectiveness of each position. The goal is to establish tailored recommendations for urodynamic testing in this specific patient population.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic practices for bladder dysfunction in patients with neurological conditions.
How similar studies have gone: While there is limited research specifically addressing this population, previous studies have indicated that position can influence urodynamic outcomes, suggesting potential for success in this novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient with MS or neurologically confirmed Parkinson's disease, with indication for urodynamic assessment - 1st assessment * Clinical overactive bladder syndrome with USP overactive bladder sub-score \> or = 4 - Age ≥18 years * In men: no prostatic hypertrophy on ultrasonography * In women: no stress urinary incontinence (SUI); USP SUI subscore ≤ 2 * Affiliated with a social security scheme (excluding AME). * Free and informed written consent Exclusion Criteria: * Opposition to the performance of a Urodynamic exam as part of treatment
Where it's running
-
Physical and Rehabilitation Medicine Pitié Salpêtrière Hospital
Paris, France, France Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Urodynamics versus videourodynamics for women with recurrent stress urinary incontinence
This trial will test whether videourodynamics or standard urodynamics before repeat surgery helps women with recurrent stress urinary incontinence get better treatment outcomes.
-
Ask Questions About Clinical Trials: A Tool to Help Patients Discuss Trials
This study tests a patient-friendly brochure called the ASQ-CT to see if it helps adults with cancer, heart disease, or neurologic conditions talk with their providers about clinical trials.
-
Postoperative breathing problems after (adeno)tonsillectomy in children with sleep apnea
See how common breathing problems are after (adeno)tonsillectomy in children with obstructive sleep apnea and which factors raise the risk.
-
Registry and natural history of epilepsy-dyskinesia syndromes
This registry will collect health data and biological samples from people of all ages who have a genetic diagnosis of epilepsy-dyskinesia syndromes to see how their genes relate to their movement and seizure symptoms over time.
-
Normal bladder and urethral pressure ranges measured with e-Sense catheters
This project will test e-Sense catheters to define normal urodynamic pressure values in adults referred for urodynamic testing, with enrollment focused on people aged 20–35 (women nulliparous) and those over 50 (women with at least one vaginal birth).
-
Investigating the health effects of harmful algal blooms
This study is trying to see how exposure to toxins from harmful algal blooms affects people's health, especially their brain and immune system, by monitoring participants over time.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.