Examining how age affects pituitary response to stimulation tests
Age-related Differences in the Response to a Combined Pituitary Stimulation Test With TRH, LHRH and ACTH
This study is testing how different age groups respond to a pituitary stimulation test to see if age affects how well the pituitary gland works.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 24 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Aalborg University Hospital Academic / other |
| Locations | 1 site (Aalborg, Northen Jutland) |
| Trial ID | NCT04572139 on ClinicalTrials.gov |
What this trial studies
This observational study investigates how different age groups respond to a combined pituitary stimulation test using TRH, LHRH, and ACTH. Participants will be categorized into three age intervals: 18-45 years, 55-80 years, and 80+ years. Each participant will undergo the same stimulation test under controlled conditions, with blood samples collected at specified intervals for analysis. The goal is to understand age-related differences in pituitary function.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy volunteers aged between 18-45 or above 55 years.
Not a fit: Patients with conditions or medications that affect pituitary response, such as hormonal birth control or thyroid disorders, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of pituitary function across different age groups, leading to better diagnostic and treatment strategies for age-related hormonal issues.
How similar studies have performed: While there may be studies on pituitary function, this specific focus on age-related differences in response to combined stimulation tests is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ages between 18-45 or above 55. * Healthy Volunteers Exclusion Criteria: * Medication or conditions affecting pituitary response (such as hormonal birth control, steriod use, thyroid disorders) * Pregnancy or birth within the last year * inability to give informed consent
Where this trial is running
Aalborg, Northen Jutland
- Department of Geriatric Medicine, Aalborg University Hospital — Aalborg, Northen Jutland, Denmark (Recruiting)
Study contacts
- Study coordinator: Johannes R Jensen, Bsc. med
- Email: johannes.j@rn.dk
- Phone: 97665185
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.