Examining hormone levels in trauma patients

A Prospective Analysis of the Gender Specific Role of Steroid Hormones on the Outcome on Patients After Polytrauma

Observational Technical University of Munich · NCT05794256

This study is trying to see how hormone levels in people who have had severe trauma affect their recovery and survival.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorTechnical University of Munich Academic / other
Locations1 site (München, Bavaria)
Trial IDNCT05794256 on ClinicalTrials.gov

What this trial studies

This observational study aims to establish a registry to investigate the role of steroid hormones in patients who have experienced severe trauma. It will measure hormone levels upon arrival at the emergency room and during the following days, while also collecting detailed health-related information through questionnaires. The primary focus is to determine how these hormone levels may influence morbidity and mortality in severely injured individuals.

Who should consider this trial

Good fit: Ideal candidates include adults over 18 who have experienced polytrauma with an Injury Severity Score of 16 or higher.

Not a fit: Patients who are pregnant, deceased upon arrival, incarcerated, or transferred from another facility may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into how hormone levels affect recovery and outcomes in trauma patients.

How similar studies have performed: While the specific approach of this study may be novel, similar studies investigating hormone levels in trauma patients have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Polytrauma with ISS≥16,
* severe traumatic brain injury (AIS ≥3)
* over the age of 18
* must reach emergency room alive

Exclusion Criteria:

* pregnant patients
* dead on arrival to the hospital
* incarcerated patients
* secondarily transferred patients

Where this trial is running

München, Bavaria

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Polytrauma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.