Examining hormonal profiles in infants with disorders of sex development
Official title: Evaluation of Minipuberty in Infants Born With a Variation in Sexual Development
Run by Centre Hospitalier Universitaire Vaudois · NCT05058781 · Data updated 2026-11-12
This study is trying to understand the hormone levels in infants with disorders of sex development to see how they compare to other babies.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 9 Months |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Centre Hospitalier Universitaire Vaudois Academic / other |
| Locations | 1 site (Lausanne, Canton of Vaud) |
| Status | Recruiting |
| Started | January 1, 2017 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2030 |
| Registry record updated | July 22, 2022 |
| Trial ID | NCT05058781 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are infants exhibiting symptoms of DSD or those born to parents with CHH.
✕Probably not a fit
Patients who are premature (less than 35 weeks of gestation) or male infants with high scrotal cryptorchidism may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on infants born with disorders of sex development (DSD) or those born to parents with congenital hypogonadism hypogonadotrope (CHH). The main objective is to evaluate the hormonal profiles during the minipuberty phase of these infants and compare them to control groups. By understanding the hormonal variations, the study aims to better characterize the underlying causes of DSD and CHH. The research will involve careful monitoring and assessment of hormonal levels in the specified infant population.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and management of infants with DSD and CHH.
How similar studies have gone: While there is ongoing research in this area, the specific focus on hormonal profiles during minipuberty in this context is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * infants born with symptoms of DSD * infants born from parents with CHH Exclusion Criteria: * premature \< 35 weeks of gestation * male infants with high scrotal cryptorchidism
Where it's running
-
Centre Hospitalier Universitaire Vaudois (CHUV)
Lausanne, Canton of Vaud, Switzerland Recruiting
Study contacts
- Principal investigator: Nelly Pitteloud, MD — Chuv
- Study coordinator: Nelly Pitteloud, MD
- Email: nelly.pitteloud@chuv.ch
- Phone: +41 79 556 27 36
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.