Examining Hepatitis E in Organ and Cell Donors
Molecular Characteristics and Prevalence of Viral Hepatitis E in Human Tissue and Cell Donors
This study is testing how common the Hepatitis E virus is in organ and cell donors to see if better testing can make transplants safer.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Sex | All |
| Sponsor | University Hospital Ostrava Academic / other |
| Locations | 1 site (Ostrava, Moravian-Silesian Region) |
| Trial ID | NCT06457438 on ClinicalTrials.gov |
What this trial studies
This study investigates the prevalence of Hepatitis E virus (HEV) in human tissue and cell donors by utilizing advanced testing methods to detect anti-HEV antibodies and HEV RNA. Researchers will analyze samples from donors to assess their health eligibility based on current legislation, which does not typically include HEV testing. The study aims to enhance donor selection processes and improve safety in organ and cell transplantation.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals indicated for organ or cell donation.
Not a fit: Patients who are not organ or cell donors will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved screening protocols for organ and cell donors, enhancing patient safety and outcomes.
How similar studies have performed: While there may be limited studies specifically targeting HEV in organ donors, similar approaches in screening for other viral infections have shown success in improving donor safety.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: \- patients indicated for organ or cell donation Exclusion Criteria: \- none
Where this trial is running
Ostrava, Moravian-Silesian Region
- University Hospital Ostrava — Ostrava, Moravian-Silesian Region, Czechia (Recruiting)
Study contacts
- Principal investigator: Hana Slepčanová, Mgr. — University Hospital Ostrava
- Study coordinator: Jiří Hynčica
- Email: jiri.hyncica@fno.cz
- Phone: 0042059737
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.