Examining heart rate and oxygen levels in patients with idiopathic pulmonary fibrosis
Differences in Heart Rate Variability and Nocturnal Blood Oxygen Saturation of Patients With Idiopathic Pulmonary Fibrosis Between at Baseline and During Acute Exacerbation
This study is testing how heart rate and oxygen levels during sleep relate to lung function and flare-ups in people with idiopathic pulmonary fibrosis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 70 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | Taipei Veterans General Hospital, Taiwan Government |
| Locations | 1 site (Taipei) |
| Trial ID | NCT06027372 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare overnight heart rate variability (HRV) and nocturnal oxygen saturation (SpO2) in patients diagnosed with idiopathic pulmonary fibrosis (IPF). It seeks to determine correlations between pulmonary function tests and HRV, as well as SpO2, and to assess whether these measurements can predict acute exacerbations in IPF patients. Participants will undergo pulmonary function tests and wear a pulse oximeter and an ECG Holter monitor during sleep to collect data. The study focuses on understanding the relationship between these physiological parameters and the progression of IPF.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 50 and older who have been diagnosed with idiopathic pulmonary fibrosis and can provide informed consent.
Not a fit: Patients under 50 years old or those with cognitive impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the monitoring and management of patients with idiopathic pulmonary fibrosis by identifying predictive markers for acute exacerbations.
How similar studies have performed: While there have been studies examining heart rate variability and oxygen saturation in other conditions, this specific approach in idiopathic pulmonary fibrosis is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * individuals meet the diagnosis of idiopathic pulmonary fibrosis * individuals agree to participate this study and sign the informed consent * individuals have cognitive and behavioral abilities Exclusion Criteria: * age less than 50 years old * individuals refuse to participate this study and sign the informed consent * individuals of unclear consciousness
Where this trial is running
Taipei
- Taipei Veterans General Hospital — Taipei, Taiwan (Recruiting)
Study contacts
- Study coordinator: Fang-Chi Lin, PhD
- Email: fclin3@vghtpe.gov.tw
- Phone: +886-937-021-807
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.