Examining genetic factors and telomere length in women with postpartum hypertension
Renalase(rs10887800) Genotyping & Leucocytes Telomere Length in Patients With Postpartum Hypertension.
This study is trying to see if certain genes and the length of specific DNA parts can help us understand why some women develop high blood pressure after giving birth.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06500351 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between Renalase(rs10887800) genotyping and leukocyte telomere length in women experiencing postpartum hypertension, whether it is a new onset or persistent condition following pregnancy. The study aims to enroll patients aged 18 and older who have been diagnosed with postpartum hypertension at Sohag University Hospitals. By analyzing genetic markers and telomere length, the research seeks to uncover potential associations that could enhance understanding of postpartum hypertension.
Who should consider this trial
Good fit: Ideal candidates for this study are women aged 18 and older diagnosed with postpartum hypertension.
Not a fit: Patients with other medical disorders during pregnancy, such as heart disease or kidney disorders, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into genetic and biological factors influencing postpartum hypertension, potentially leading to improved management strategies.
How similar studies have performed: While this specific approach is novel, similar studies exploring genetic factors in hypertension have shown promise in other contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who are18 years or above, and have a diagnosis of postpartum hypertension(regardless of where they received their antenatal care) attended to Sohag university hospitals Exclusion Criteria: * All pregnant women with medical disorders in pregnancy other than Hypertensive disorders during pregnancy (e.g., sickle cell disease, heart disease, kidney and other connective tissues disorders) will be excluded from the study. Also we excluded measurements taken during scheduled or unscheduled surgical encounters given potential for interaction with anesthetic agents
Where this trial is running
Sohag
- Sohag university hosoital — Sohag, Egypt (Recruiting)
Study contacts
- Principal investigator: Amera Morad Foad, assistant professor — Sohag University
- Study coordinator: Amera Morad Foad, assistant professor
- Email: ameramoradfoad@gmail.com
- Phone: +201006591449
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.