Examining gender differences in heart recovery after a heart attack
Disparities in Myocardial Infarction Remodeling According to Gender
NA · University Hospital, Angers · NCT06343844
This study is trying to see how heart recovery after a heart attack is different for men and women to help improve treatment for everyone.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 1650 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Angers (other gov) |
| Locations | 1 site (Angers) |
| Trial ID | NCT06343844 on ClinicalTrials.gov |
What this trial studies
This study investigates how myocardial infarction affects cardiac remodeling differently in men and women, focusing on the poorer prognosis observed in female patients. It involves non-invasive imaging techniques to assess changes in left ventricular volumes and function following the first ST-segment elevation myocardial infarction. The study aims to establish a biorepository and registry to better understand these disparities and improve patient outcomes. Participants will be monitored over time to gather data on their cardiac health post-infarction.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 who have experienced their first ST-segment elevation myocardial infarction and are enrolled in the RIMA registry.
Not a fit: Patients who are not fluent in French, pregnant, or have legal restrictions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies and outcomes for women recovering from myocardial infarction.
How similar studies have performed: While there is ongoing research into gender differences in cardiac health, this specific focus on myocardial infarction remodeling in women is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years * First myocardial infarction with ST-segment elevation during the hospital phase * Coronary angiography performed within 72 hours of the infarction * Inclusion in the RIMA registry * Patient affiliated or beneficiary of a social security scheme; Signature of informed consent Exclusion Criteria: * Patients already enrolled in the study * Poor understanding of the French language * Pregnant, breastfeeding, or postpartum women * Individuals deprived of liberty by judicial or administrative decision; Individuals receiving psychiatric care under coercion * Individuals subject to a legal protection measure; Individuals incapable of giving consent
Where this trial is running
Angers
- University Hospital, Angers — Angers, France (RECRUITING)
Study contacts
- Study coordinator: LOIC BIERE, PHD
- Email: LoBiere@chu-angers.fr
- Phone: 02 41 35 36 37
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Myocardial Infarction, Ventricular Remodeling, Non-Interventional Registry, Biorepository Establishment