Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Examining gender differences in heart recovery after a heart attack

Official title: Disparities in Myocardial Infarction Remodeling According to Gender

Run by University Hospital, Angers · NCT06343844 · Data updated 2026-11-12

This study is trying to see how heart recovery after a heart attack is different for men and women to help improve treatment for everyone.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment1650 (estimated)
SponsorUniversity Hospital, Angers
Government
Locations1 site (Angers)
StatusRecruiting
StartedJuly 15, 2024
Main results expectedNovember 1, 2039
Study endsSeptember 1, 2040
Registry record updatedFebruary 9, 2026
Trial IDNCT06343844 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 who have experienced their first ST-segment elevation myocardial infarction and are enrolled in the RIMA registry.

Probably not a fit

Patients who are not fluent in French, pregnant, or have legal restrictions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how myocardial infarction affects cardiac remodeling differently in men and women, focusing on the poorer prognosis observed in female patients. It involves non-invasive imaging techniques to assess changes in left ventricular volumes and function following the first ST-segment elevation myocardial infarction. The study aims to establish a biorepository and registry to better understand these disparities and improve patient outcomes. Participants will be monitored over time to gather data on their cardiac health post-infarction.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment strategies and outcomes for women recovering from myocardial infarction.

How similar studies have gone: While there is ongoing research into gender differences in cardiac health, this specific focus on myocardial infarction remodeling in women is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \> 18 years
* First myocardial infarction with ST-segment elevation during the hospital phase
* Coronary angiography performed within 72 hours of the infarction
* Inclusion in the RIMA registry
* Patient affiliated or beneficiary of a social security scheme; Signature of informed consent

Exclusion Criteria:

* Patients already enrolled in the study
* Poor understanding of the French language
* Pregnant, breastfeeding, or postpartum women
* Individuals deprived of liberty by judicial or administrative decision; Individuals receiving psychiatric care under coercion
* Individuals subject to a legal protection measure; Individuals incapable of giving consent

Where it's running

  • University Hospital, Angers
    Angers, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.