Examining features of melanocytic tumors in the central nervous system

Clinical, Radiological, Histological and Molecular Features of a Cohort of Melanocytic Tumors of the Central Nervous System

Central Hospital, Nancy, France · NCT05984108

This study is trying to better understand rare brain tumors that come from skin cells to help doctors tell them apart from other similar conditions.

Quick facts

Study typeObservational
Enrollment50 (estimated)
SexAll
SponsorCentral Hospital, Nancy, France (other)
Locations1 site (Nancy)
Trial IDNCT05984108 on ClinicalTrials.gov

What this trial studies

This observational study focuses on primary melanocytic tumors of the central nervous system, which are rare and arise from leptomeningeal melanocytes. It aims to differentiate these tumors from other conditions, such as metastatic melanoma and malignant melanotic nerve sheath tumors, through comprehensive assessments including dermatological examinations and molecular characterizations. The study will analyze clinical, radiological, histological, and molecular features to improve diagnostic accuracy and understanding of these tumors.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with a primary meningeal melanocytic tumor.

Not a fit: Patients with metastatic extrameningeal melanoma will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the diagnostic process for patients with melanocytic tumors of the central nervous system, leading to more accurate treatment plans.

How similar studies have performed: While this study addresses a rare condition, similar approaches in characterizing tumors have shown promise in improving diagnostic accuracy in other contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient with a primitive meningeal melanocytic tumor

Exclusion Criteria:

* Patient with metastatic extrameningeal melanoma

Where this trial is running

Nancy

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Meningeal Melanocytoma, Meningeal Melanomatosis, Meningeal Melanocytosis, Meningeal Melanoma

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.