Examining Eosinophil Function in Lung Diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with eosinophilic pulmonary diseases, such as eosinophilic granulomatosis with polyangiitis and idiopathic hypereosinophilic syndrome. It aims to identify different eosinophil subtypes in peripheral blood by analyzing surface protein expression. The study seeks to understand how these subtypes vary among patients with different eosinophilic conditions, which may help guide treatment decisions in the future.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* For Healthy Volunteers: healthy volunteers matching the age and gender of the study subjects
* For EPD: ① Persistent eosinophil count increase\>1500 per cubic millimeter for more than 6 months. ② Lack of evidence of a secondary cause of eosinophilia is required. ③ Signs and symptoms of end-organ damage presumed to be secondary to eosinophilia

Exclusion Criteria:

* Patients with concurrent definitive pulmonary infections, malignancies, or other parenchymal lung diseases;
* Patients who are unable or unwilling to cooperate with the collection of clinical information (e.g., due to mental disorders, memory impairments, etc.);
* Patients who are unable to provide informed consent.

Where it's running

• Peking Union Medical College Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Juhong Shi, M.D
• Email: shijh@pumch.cn
• Phone: +8613701178492

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.