Examining Doppler Measurements in Obese Pregnant Women
The Effect of Maternal Obesity on Umbilical and Uterine Artery Doppler in Term Pregnancy : a Cross-sectional Study
This study looks at how blood flow in the uterine artery differs between obese and normal-weight pregnant women to see if it helps explain complications during pregnancy.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 240 (estimated) |
| Ages | 20 Years to 35 Years |
| Sex | Female |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut) |
| Trial ID | NCT06644911 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the role of Doppler measurements of the uterine artery in pregnant women with obesity. It aims to understand how maternal obesity may contribute to complications during pregnancy, such as pre-eclampsia and fetal growth restriction, by assessing uterine vascular changes. The study focuses on women with singleton pregnancies at term, comparing those with obesity to those of normal weight to identify potential differences in vascular impedance. The findings could provide insights into the management of high-risk pregnancies associated with obesity.
Who should consider this trial
Good fit: Ideal candidates for this study are obese women with a singleton pregnancy at 37 weeks or more gestation and no significant maternal or fetal complications.
Not a fit: Patients with conditions such as placenta previa, preeclampsia, or those requiring urgent termination of pregnancy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring and management strategies for obese pregnant women, potentially reducing complications.
How similar studies have performed: Other studies have shown the utility of Doppler measurements in high-risk pregnancies, suggesting that this approach is supported by existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Singleton pregnancy 2. Gestational age ≥ 37 weeks 3. Absence of fetal structural abnormalities 4. Absence of maternal comorbidities and/or complications. 5. Obese women (BMI ≥ 30 kg/m2) \[11\]. 6. Normal weight (BMI 18.5-24.9) \[11\]. Exclusion Criteria: 1. Placenta previa 2. Women with antepartum hemorrhage. 3. Smokers and alcohol consumers 4. Preeclampsia 5. Diabetes mellitus 6. Women need urgent termination of pregnancy.
Where this trial is running
Asyut
- Woman's Health Hospital - Assiut university — Asyut, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohammed Khairy Ali, MD
- Email: mohammedelkosy@aun.edu.eg
- Phone: 01005537951
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.