Examining CPK Levels After Laparoscopic Gallbladder Surgery and Pain Management Techniques
Official title: Does Postoperative Analgesic Modalities Effect Blood Creatin Phosphokinase Levels After Laparoscopic Cholecystectomy Surgery?
Run by Samsun University · NCT06508177 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing whether different pain management techniques during gallbladder surgery affect muscle health by measuring a specific enzyme in patients before and after the operation.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Samsun University Academic / other |
| Locations | 1 site (Samsun) |
| Trial ID | NCT06508177 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients classified as ASA 1-3 who are scheduled for laparoscopic cholecystectomy under general anesthesia.
✕Probably not a fit
Patients with conditions such as morbid obesity, local anesthetic allergies, myopathies, or significant comorbidities like heart or liver diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the levels of plasma creatine phosphokinase (CPK) in patients undergoing laparoscopic cholecystectomy, focusing on the potential myotoxicity associated with different analgesic modalities, particularly interfascial plane blocks. Over a three-month period, eligible patients will have their CPK levels measured preoperatively and at 6 and 24 hours postoperatively. The study will analyze the data to determine if there is a correlation between the type of analgesia used and CPK levels, which may indicate muscle damage. The findings could provide insights into the safety and efficacy of regional anesthesia techniques in surgical settings.
Why it matters
Potential benefit: If successful, this study could enhance postoperative pain management strategies while minimizing the risk of muscle damage in patients undergoing laparoscopic surgery.
How similar studies have gone: While there have been studies on myotoxicity related to local anesthetics, this specific investigation into CPK levels following interfascial plane blocks in laparoscopic surgery is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA 1-3 * Laparoscopic cholecystectomy * under General Anesthesia Exclusion Criteria: * Morbidly obesity or cachexia * local anesthetic allergies * myopathies * coagulopathies * Obstructive sleep apne syndrome * hearth diseases * liver diseases * kidney diseases * thyroid-parathyriod dieseas * hiperlipidemias using Statins(HMG-CoA reductase inhibitors) * pregnancy
Where it's running
-
Samsun University
Samsun, Turkey Recruiting
Study contacts
- Study coordinator: Murat Unal
- Email: murat.unal@yahoo.com
- Phone: +903623111500
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.