Examining brain activation during word processing using TMS

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how the left anterior temporal lobe (ATL) activates during lexical processing tasks using Transcranial Magnetic Stimulation (TMS). Participants will engage in three tasks: determining if a stimulus is a real word or pseudoword, identifying if a word refers to an action or an object, and judging the divisibility of numbers. TMS will be applied at specific time points after stimulus onset to measure the effects on reaction times and accuracy. The goal is to better understand the timing of semantic processing in the brain.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participants must be within the ages of 18 to 40
* Native speakers of English

Exclusion Criteria:

* Potential participants with a clinically reported history of dementia, alcohol abuse, psychiatric or neurological disorders, traumatic brain injury, or extensive vision or hearing problems that prevents them from performing the tasks
* Contraindication to TMS, determined by a standard TMS screening form
* Contraindication to MRI, determined by a standard MRI screening form
* Left handed participants

Where it's running

• Prisma Health Richland
  Columbia, South Carolina, United States Recruiting

Study contacts

• Study coordinator: Rutvik H Desai, PhD
• Email: rutvik@sc.edu
• Phone: 8032617149

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.