Examining antibiotic use after facial fractures
Antibiotic Use in Facial Fracture Post Injury
This study looks at whether giving patients antibiotics for 3 days or 5 days after facial fracture surgery affects their chances of getting infections.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Methodist Health System Academic / other |
| Locations | 1 site (Dallas, Texas) |
| Trial ID | NCT04925531 on ClinicalTrials.gov |
What this trial studies
This research involves a retrospective chart review of trauma patients with facial fractures treated at Methodist Health System from 2010 to 2015. The study aims to compare clinical outcomes based on the duration of postoperative antibiotic administration, specifically looking at groups receiving antibiotics for either 3 days or 5 days. By analyzing patient records, the study seeks to determine if the length of antibiotic use impacts the incidence of infectious complications following facial fracture surgeries.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have sustained blunt or penetrating facial injuries.
Not a fit: Patients who are pregnant or breastfeeding will not benefit from this study due to exclusion criteria.
Why it matters
Potential benefit: If successful, this study could help establish optimal antibiotic protocols to reduce infection rates in patients with facial fractures.
How similar studies have performed: Previous studies have shown significant reductions in infection rates with antibiotic prophylaxis in maxillofacial surgery, indicating a foundation for this research approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male and female patient's ≥ 18 years of age. * Blunt and penetration injury. Exclusion Criteria: * Pregnant and breast feeding women.
Where this trial is running
Dallas, Texas
- Methodist Dallas Medical Center — Dallas, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Michael Truitt, M.D. — The Methodist Hospital Research Institute
- Study coordinator: Crystee Cooper, DHEd
- Email: CrysteeCooper@mhd.com
- Phone: 214-947-1280
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.