Examining airway changes in young patients with Class II Division 2 malocclusion after orthodontic treatment

Changes in the Sagittal Pharyngeal Airway Dimension Following Leveling and Alignement in Class II Division 2 Patients: A Prospective Clinical Trial

Not applicable Interventional University of Alexandria · NCT06602518

This study is testing how orthodontic treatment affects the airway size and jaw position in teenagers aged 12 to 16 with a specific type of bite problem.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment27 (estimated)
Ages12 Years to 16 Years
SexAll
SponsorUniversity of Alexandria Academic / other
Locations1 site (Alexandria)
Trial IDNCT06602518 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the changes in the sagittal pharyngeal airway dimension and mandibular position in patients diagnosed with Class II Division 2 malocclusion following the leveling and alignment phase of orthodontic treatment. The participants will be adolescents aged 12 to 16 years who meet specific inclusion criteria, including having a deep bite and full permanent dentition. The study will involve measuring airway dimensions before and after the orthodontic intervention to assess any significant changes.

Who should consider this trial

Good fit: Ideal candidates for this study are adolescents aged 12 to 16 years with Class II Division 2 malocclusion and specific dental characteristics.

Not a fit: Patients who have previously undergone orthodontic treatment or have severe TMJ issues or craniofacial anomalies may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into how orthodontic treatment affects airway dimensions, potentially improving breathing and overall health in affected patients.

How similar studies have performed: While there may be limited studies specifically targeting this demographic and condition, similar orthodontic interventions have shown promising results in improving airway dimensions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Class II/2 subjects as per the British Standard Institute Classification.
* Age ranging from 12-16 years, with Cervical Vertebral Maturational Index (CVMI) stages 4, and 5.
* Contact between maxillary and mandibular incisors, with the presence of a deep bite of at least 70%.
* Full permanent dentition, aside from the third molars

Exclusion Criteria:

* Previous orthodontic treatment.
* Patients with severe transverse problems, pain and/or clicking sound in the temporomandibular joint (TMJ).
* Patients with craniofacial anomalies or diagnosed syndromes

Where this trial is running

Alexandria

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Class II Division 2 Malocclusion
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.