Evaluation of treatment for univentricular heart defects

Evaluation of the Standard Data Collected as Part of the Erlangen Protocol for the Treatment and Monitoring of Patients With Univentricular Heart Defects in Terms of the Fontan Procedure

NA · University of Erlangen-Nürnberg Medical School · NCT05620030

This study is testing a new treatment approach for children with univentricular heart defects to see if it can improve their care and lower the risk of death.

Quick facts

PhaseNA
Study typeInterventional
Enrollment30 (estimated)
Ages6 Years to 60 Years
SexAll
SponsorUniversity of Erlangen-Nürnberg Medical School (other)
Locations1 site (Erlangen)
Trial IDNCT05620030 on ClinicalTrials.gov

What this trial studies

This study focuses on patients with univentricular heart defects, which are complex congenital malformations requiring multiple surgical interventions. The treatment typically involves three operations and various diagnostic procedures within the first few years of life to establish Fontan circulation. The study follows a clinical protocol developed in Erlangen that includes both invasive and non-invasive diagnostic examinations, such as cardiac catheterization and magnetic resonance imaging, to monitor patient outcomes. The aim is to improve the management and reduce mortality rates associated with these heart defects.

Who should consider this trial

Good fit: Ideal candidates for this study are infants and young children diagnosed with congenital univentricular heart defects requiring multi-stage treatment.

Not a fit: Patients with congenital heart defects that do not fall under the univentricular category may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment protocols and reduced mortality rates for patients with univentricular heart defects.

How similar studies have performed: Other studies have shown success in managing univentricular heart defects using standardized treatment protocols, indicating that this approach is both tested and promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* congenital heart defect of the univentricular type and the clinical necessity of a multi-stage treatment in terms of the Fontan procedure.

Exclusion Criteria:

* no exclusion criteria

Where this trial is running

Erlangen

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Univentricular Heart

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.