Evaluation of new zirconia crowns for dental restoration

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical evaluation investigates the performance of a new monolithic zirconia material designed for chairside CAD/CAM crowns. The study involves a randomized, prospective, longitudinal approach where crowns will be luted using either self-adhesive or conventional cement. Participants will have their crowns evaluated over a two-year period to assess durability and effectiveness in restoring dental function. The trial focuses on patients with specific dental conditions requiring full crown restorations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* at least 18 years of age
* at least one carious lesion, defective restoration, or fractured portion of the tooth to be restored on a maxillary or mandibular premolar or molar tooth - Each lesion, fracture, or defective restoration should exhibit sufficient size or loss of tooth structure requiring a full crown restoration.
* tooth should have at least one opposing tooth in occlusion and one adjacent tooth with an intact proximal contact
* No more than ten teeth that are endodontically treated may be included in the study, equally divided between the two groups of crowns. All remaining teeth in the study will test vital and be asymptomatic at the beginning of treatment.
* No more than two restorations will be placed per patient

Exclusion Criteria:

* Sensitive teeth
* Teeth with a history of direct or indirect pulp capping procedures
* Patients with significant untreated dental disease to include periodontitis and/or rampant caries
* Women who self-report that they are possibly pregnant, pregnant, or lactating, as elective dental treatment is not indicated at these times
* Patients with a self-reported history of allergies to the materials to be used in the study including composite resin cements or zirconia restorative materials
* Patients unable to return for the recall appointments

Where it's running

• University of Michigan School of Dentistry
  Ann Arbor, Michigan, United States Recruiting

Study contacts

• Principal investigator: Dennis J. Fasbinder, DDS — University of Michigan
• Study coordinator: Dennis J. Fasbinder, DDS
• Email: djfas@umich.edu
• Phone: (734) 647-4450

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.